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. 2024 Jan 6;9(3):3642–3668. doi: 10.1021/acsomega.3c07655

Table 2. Evaluating Body Weight and Weight Gain Percentage in Acute and Subacute Toxicity Studies of Rats with Fip.Cr Treatmenta.

  acute toxicity
subacute toxicity
parameters normal control group 1000 mg/kg 1500 mg/kg 2000 mg/kg normal control group 125 mg/kg 250 mg/kg 500 mg/kg
Body Weight
initial weight (g) 191 ± 18.40 187 ± 12.83 193.2 ± 14.92 188 ± 10.54 194.2 ± 14.72 185.4 ± 11.28 183.8 ± 7.29 185.8 ± 6.72
7th day (g) 202 ± 21.45 196.6 ± 12.01 197.8 ± 17.88 193.4 ± 11.63 201.4 ± 16.99 195 ± 10.49 191 ± 10.98 192 ± 7.62
14th day (g) 210.8 ± 23.48 205.4 ± 13.35 204.6 ± 17.56 200.6 ± 12.42 210 ± 18.43 200 ± 12.69 202.2 ± 11.34 203.4 ± 6.19
21st day (g)         222.8 ± 16.86 210.2 ± 12.87 210.8 ± 9.731 213.4 ± 10.24
28th day (g)         236.8 ± 16.90 219.6 ± 13.26 222.4 ± 11.48 226 ± 9.43
Body Weight Gain
7th day (%) 5.69 ± 2.15 5.19 ± 2.20 2.30 ± 1.8 2.87 ± 2.19 3.66 ± 1.48 5.23 ± 2.57 3.88 ± 2.75 3.34 ± 1.89
14th day (%) 10.27 ± 3.13 9.91 ± 3.28 5.88 ± 2.95 6.73 ± 3.96 8.06 ± 2.25 7.89 ± 2.99 9.99 ± 4.10 9.53 ± 2.62
21st day (%)         14.73 ± 1.49 13.41 ± 3.59 14.74 ± 4.61 14.98 ± 7.12
28th day (%)         21.98 ± 2.47 18.51 ± 4.58 21.01 ± 4.4 21.75 ± 6.53
a

(n = 5) Values are reported as mean ± standard deviation. One-way ANOVA followed by Dunnett’s t test for statistical analysis. *p < 0.05 compared to the control group.