Table 3. Evaluation of Absolute Organ Weight (g) and Relative Organ Weight Percentage in Acute and Subacute Toxicity Studies Treatment of Rats with Fip.Cr^a.

		acute toxicity				subacute toxicity
organ		normal control group	1000 mg/kg	1500 mg/kg	2000 mg/kg	normal control group	125 mg/kg	250 mg/kg	500 mg/kg
heart	absolute	0.76 ± 0.12	0.76 ± 0.04	0.71 ± 0.09	0.70 ± 0.13	0.80 ± 0.15	0.76 ± 0.15	0.71 ± 0.11	0.80 ± 0.10
	relative	0.36 ± 0.02	0.37 ± 0.01	0.35 ± 0.02	0.35 ± 0.05	0.34 ± 0.05	0.35 ± 0.05	0.32 ± 0.04	0.35 ± 0.03
kidney	absolute	0.84 ± 0.19	0.82 ± 0.07	0.80 ± 0.13	0.76 ± 0.10	0.90 ± 0.26	0.78 ± 0.12	0.86 ± 0.19	0.97 ± 0.20
	relative	0.39 ± 0.04	0.40 ± 0.01	0.39 ± 0.04	0.38 ± 0.03	0.38 ± 0.09	0.36 ± 0.05	0.39 ± 0.07	0.43 ± 0.07
liver	absolute	6.20 ± 1.3	6.28 ± 1.3	6.10 ± 1.2	5.42 ± 0.84	6.82 ± 1.43	6.25 ± 1.14	7.19 ± 0.56	7.02 ± 0.87
	relative	2.93 ± 0.45	3.04 ± 0.49	2.97 ± 0.36	2.70 ± 0.36	2.86 ± 0.42	2.85 ± 0.48	3.24 ± 0.29	3.11 ± 0.35
spleen	absolute	0.58 ± 0.20	0.54 ± 0.11	0.49 ± 0.11	0.50 ± 0.12	0.50 ± 0.13	0.44 ± 0.13	0.48 ± 0.09	0.53 ± 0.17
	relative	0.27 ± 0.07	0.26 ± 0.03	0.24 ± 0.04	0.25 ± 0.05	0.21 ± 0.04	0.20 ± 0.05	0.22 ± 0.04	0.23 ± 0.07
lungs	absolute	1.54 ± 0.45	1.71 ± 0.39	1.65 ± 0.32	1.31 ± 0.37	1.92 ± 0.28	1.49 ± 0.20	1.56 ± 0.35	1.73 ± 0.22
	relative	0.72 ± 0.14	0.83 ± 0.13	0.80 ± 0.10	0.65 ± 0.15	0.81 ± 0.06	0.68 ± 0.05	0.70 ± 0.14	0.76 ± 0.07

^aThe presented values (n = 5) are the mean ± standard deviation. For statistical analysis, one-way ANOVA was followed by Dunnett’s t test. *p < 0.05 concerning the control group.