Table 3.
Baseline characteristics stratified by CTI
| Variables | CTI < 4.71 | CTI ≥ 4.71 | P-value |
|---|---|---|---|
| (n = 763) | (n = 649) | ||
| Sex (%) | 0.066 | ||
| Male | 466(61.1) | 428(65.9) | |
| Female | 297(38.9) | 221(34.1) | |
| Age (mean (SD)) | 58.27(11.66) | 60.84(10.88) | < 0.001 |
| BMI (mean (SD)) | 20.89(3.07) | 21.17(3.31) | 0.105 |
| Tumor stage (%) | < 0.001 | ||
| I | 52(6.8) | 31(4.8) | |
| II | 174(22.8) | 58(8.9) | |
| III | 255(33.4) | 161(24.8) | |
| IV | 282(37.0) | 399(61.5) | |
| Tumor.type (%) | < 0.001 | ||
| Lung cancer | 169(22.1) | 213(32.8) | |
| Gastric cancer | 212(27.8) | 102(15.7) | |
| Other digestive cancers | 53(6.9) | 66(10.2) | |
| Esophageal cancer | 76(10.0) | 53(8.2) | |
| Colorectal cancer | 157(20.6) | 120(18.5) | |
| Breast cancer | 28(3.7) | 18(2.8) | |
| Female reproductive cancer | 19(2.5) | 30(4.6) | |
| Urological cancer | 12(1.6) | 17(2.6) | |
| Nasopharyngeal cancer | 26(3.4) | 8(1.2) | |
| Other cancer | 11(1.4) | 22(3.4) | |
| Surgery, yes (%) | 418(54.8) | 266(41.0) | < 0.001 |
| Radiotherapy, yes (%) | 62(8.1) | 74(11.4) | 0.047 |
| Chemotherapy, yes (%) | 418(54.8) | 383(59.0) | 0.122 |
| Tch, mmol/L (mean (SD)) | 4.46(1.04) | 4.41(1.29) | 0.396 |
| TG (mean (SD)) | 1.15(0.49) | 1.53(1.07) | < 0.001 |
| CRP (mean (SD)) | 3.64(3.05) | 50.33(51.47) | < 0.001 |
| CTI (mean (SD)) | 4.14(0.41) | 5.32(0.42) | < 0.001 |
| Glu (mean (SD)) | 5.33(1.14) | 6.05(2.21) | < 0.001 |
| Smoking, yes (%) | 358(46.9) | 353(54.4) | 0.006 |
| drinking, yes (%) | 196(25.7) | 157(24.2) | 0.558 |
| diabetes, yes (%) | 45(5.9) | 94(14.5) | < 0.001 |
| hypertension, yes (%) | 115(15.1) | 140(21.6) | 0.002 |
| CHD, yes (%) | 29(3.8) | 37(5.7) | 0.119 |
| KPS (mean (SD)) | 85.54(11.42) | 79.63(17.39) | < 0.001 |
| QC30 (mean (SD)) | 47.85(12.87) | 53.36(13.62) | < 0.001 |
| ECOG PS (%) | < 0.001 | ||
| < 2 | 712(93.3) | 522(80.4) | |
| ≥ 2 | 51(6.7) | 127(19.6) | |
| PGSGA (%) | 0.003 | ||
| Well-nourished | 8.89(3.92) | 10.81(4.67) | |
| Malnutrition | 722(94.6) | 635(97.8) | |
| Nutrition intervention, yes (%) | 160(21.0) | 172(26.5) | 0.017 |
| TSF (mean (SD)) | 13.52(6.64) | 13.53(7.03) | 0.978 |
CTI CRP-TyG index, CRP C-reactive protein, TyG triglyceride-glucose index, BMI body mass index, CHD coronary heart disease, KPS karnofsky performance status, EORTC QLQ-C30 The European Organization for Research and Treatment of Cancer (EORTC), Quality of Life Questionnaire-Core 30 (QLQ-C30), ECOG PS eastern cooperative oncology group performance status, PGSGA Patient Generated Subjective Global Assessment, TSF triceps skinfold thickness