Table 1.
Abbreviation List
| AA | arachidonic acid |
| AC | adenylate cyclase |
| ADP | adenosine diphosphate |
| AKT | Ak strain transforming serine/threonine kinase 1 |
| AMK | AMP-activated protein kinases |
| ATP | adenosine 5′-triphosphate |
| BAI3 | brain-specific angiogenesis inhibitor 3 |
| Ca2+ | calcium ion |
| [Ca2+]c | cytosolic Ca2+ concentration |
| cAMP | cyclic adenosine monophosphate |
| CICR | Ca2+-induced calcium release |
| C1ql3 | complement 1q-like-3 |
| COX | cyclooxygenase |
| cPLA2 | cytosolic phospholipase A2 |
| cSIS | cAMP-stimulated insulin secretion |
| CTRP13 | C1q/TNF-related protein 13 |
| CUB | complement C1r/C1s, Uegf, Bmp1 |
| CREB | cAMP-response element binding protein |
| CYP | cytochrome P450 |
| DAG | diacylglyceride |
| DGLA | dihomo-γ-linolenic acid |
| DHA | docosahexaenoic acid |
| DHET | dihydroxyeicosatrienoic acids |
| DIO | diet-induced obesity |
| DP2 | prostaglandin D2 receptor |
| EET | epoxyeicosatrienoic acids |
| EP | PGE2 receptor |
| EPA | eicosapentaenoic acid |
| Epac | exchange protein activated by cyclic-AMP |
| FFAR1 | free fatty acid receptor 1 |
| FOXO1 | forkhead box protein O1 |
| FRET | fluorescence resonance energy transfer |
| GAIN | G-protein-coupled receptor (GPCR) autoproteolysis-inducing domain |
| GEF | guanine nucleotide exchange factor |
| GRP | G protein-coupled receptor |
| Gs | Gs protein |
| Gi | Gi protein |
| Gα | Gs alpha subunit |
| GIP | glucose-dependent insulinotropic polypeptide |
| GLP1 | glucagon-like peptide-1 |
| GPCR | G-protein coupled receptor |
| GPE | glycerophosphatidylethanolamine |
| GPR120 | G-protein coupled receptor 120 |
| GPR119 | G-protein coupled receptor 119 |
| GPR44 | G-protein coupled receptor 44 |
| GPS | glycerophosphatidylserine |
| GSIS | glucose-stimulated insulin secretion |
| GWAS | genome-wide association studies |
| HEPE | hydroxyeicosapentaenoic acid |
| HETE | hydroxyeicosatetraenoic acid |
| HFD | high-fat diet |
| IAPP | islet amyloid polypeptide |
| IG | insulin granule |
| IGT | impaired glucose tolerance |
| IP3 | inositol trisphosphate |
| iPLA2 | Ca2+-independent phospholipase A2 |
| iPLA2β | β-isoform of Ca2+-independent phospholipase A2 |
| iPLA2ββKO | select-deficiency of iPLA2β in β-cells |
| iPLA2ββTG | select overexpression of iPLA2β in β-cells |
| JNK1 | c-Jun N-terminal kinase |
| K+ | potassium ion |
| KATP | potassium-sensitive ATP-channel |
| Kv2.1 | delayed rectifier K+-channel |
| LOX | lipo-oxygenase |
| MØ | macrophages |
| M1 | inflammatory MØ phenotype |
| MAFA1 | MAF BZIP Transcription Factor A |
| MUFA | mono-unsaturated fatty acid |
| Munc | mammalian uncoordinated-18 |
| NEFA | nonesterified fatty acid |
| NKX6.2 | NK6 Homeobox 2 |
| PDE | phosphodiesterase |
| PDXl | pancreatic and duodenal homeobox l |
| PDZ | modular protein-protein interacting domain |
| PKA | protein kinase A |
| PGE2 | prostaglandin E2 |
| PGI2 | prostaglandin I2 |
| PKC | protein kinase C |
| PLA2 | phospholipase A2 |
| PLCε | phospholipase C-epsilon |
| PUFAs | polyunsaturated fatty acids |
| P450 | cytochrome P450 |
| PGD2 | prostaglandin D2 |
| PUFA | polyunsaturated fatty acid |
| Rab | Ras superfamily of small G proteins |
| Rap | receptor-associated protein |
| RIα | R-subunit |
| RIM | Rab-interacting molecules |
| RRP | readily releasable pool |
| sEH | soluble epoxide hydrolase |
| siRNA | small interfering RNA |
| SL | sphingolipid |
| SMase | sphingomyelinase |
| SNAP | synaptosomal-associated protein |
| SNARE | soluble N-ethylmaleimide-sensitive factor attachment protein receptor |
| S1P | sphingosine-1-phosphate |
| sPLA2 | secretory phospholipase A2 |
| SU | sulfonylurea |
| SUR1 | sulfonylurea receptor 1 |
| T2D | type 2 diabetes |
| TF | transcription factor |
| Tnf | tumor necrosis factor |
| TORC2 | transducer of regulated CREB activity-2 |
| Vamp2 | vesicle-associated membrane protein 2 |
| VDCC | voltage-dependent Ca2+-channels |