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. Author manuscript; available in PMC: 2024 Jan 25.
Published in final edited form as: Mol Cell Biochem. 2020 Jan 7;466(1-2):1–15. doi: 10.1007/s11010-019-03680-y

Fig. 1. GYY reversed Ang-II-induced altered PAI-1 and tPA expression in MCs and MGECs.

Fig. 1

Mouse (a) mesangial cells (MCs), and (b) glomerular endothelial cells (MGECs) were treated with or without Ang-II for 48 h. GYY (GYY4137) was added 1 h prior to Ang-II treatment. The expressions of PAI-1 (~48 kDa) and tPA (~70 kDa) protein were measured by Western blotting using respective primary and HRP-conjugated appropriate secondary antibodies. GAPDH was used as a loading control. Data are presented as mean ± SEM, n = 9 independent experiments / group; *p <0.05 vs control, †p <0.05 vs Ang-II.