Both cells, MCs (a) and MGECs (b) were treated with or without Ang-II for 48 h. GYY (GYY4137) was added 1 h prior to the Ang-II treatment. Cells were immunostained against MMP-14 (green) and nuclei counterstained with DAPI (blue). (c) and (d) summarized data of MMP-14 expression in MCs and MGECs, respectively. Data are presented as mean ± SEM, n=9 independent experiments / group. *p <0.05 vs control, †p <0.05 vs Ang-II. Scale bar, 20 μm; magnification 60X.