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. 2023 Dec 6;52(2):e11. doi: 10.1093/nar/gkad1146

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Evaluation of cross-feature correlation preservation. (A) Reference signal cross-feature correlation matrix. (B) Raw signal cross-feature correlation matrix in target neutrophil (NEU) cell type. (C) JMnorm-normalized signal cross-feature correlation matrix in target NEU cell type. (D) A boxplot of MSEs between human target and reference correlation matrices for the seven normalization methods. (E) A boxplot of MSEs between correlation matrices of mouse target cell types and the human reference for the six normalization methods.