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Photographs of hairless SKH1 mice 24 h after infection with 106 CFU of either the SLS-producing wild-type MGAS166s (A) or the SLS-deficient Tn916 mutant SBNH5 (B). A well-demarcated zone of induration with centralized necrosis is visible on the right flank of the mouse infected with MGAS166s. No necrosis was seen in mice infected with SBNH5.
