Table 1. Description and summary of the results of the studies included in the systematic review and meta-analysis.
Authors, year | Study size | Country | Design | Relaxation, type and duration applied | Time outcome measured | Outcome | Results | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Relaxation | Control | ||||||||||
1. Bastani F, et al. 2005 | EG:55 CG:55 |
Iran | RCT | Progressive muscle relaxation (PMR) and breathing exercise for 7 weeks between gestational age of 14 and 28 weeks | Immeditely before and after the 7th week of intervention. Made goup comparison | Stress—percieved stress scale (PSS) | PSS points | 24.4 ± 5.8 | 37.5 ± 5.7* | ||
State anxiety—state anxiety trait inventory (S-STAI) | S-STAI points | 22.7 ± 7.4 | 38.5 ± 5.7* | ||||||||
Trait anxiety: (T-STAI) | T-STAI, points | 22.7± 7.4 | 38.5 ±5.7* | ||||||||
2. Bastani F, et al. 2006 | EG:55 CG:55 |
Iran | RCT | Progressive muscle relaxation (PMR) and breathing exercise for 7 weeks between gestational age of 14 and 28 weeks | Immeditely before and after intervention and at birth done for goup comparisons | Birth weight (BW) | grams | 3168 ± 42 | 2883 ± 6* | ||
Low BW | n (%) | 3 (5.8) | 14 (26.9)* | ||||||||
Gestational age | week | 38 ± 5.9 | 38 ± 4.40 ‡ | ||||||||
Preterm birth | n (%) | 1 (1.9) | 5 (9.8) ‡ | ||||||||
Mode of delivery; n (%) | Abnormal | 11 (21.2) | 25 (48.1)* | ||||||||
SVD | 41 (78.8) | 27 (39.7)* | |||||||||
C/S | 8 (15.4) | 21 (40.40)* | |||||||||
Instrumental | 3 (5.8) | 4 (7.70)* | |||||||||
3. Chuntharapat S, et al. 2008 | EG:33 CG:33 |
Thailand. | RCT | Yoga 1 hour weekly for 6 Weeks at 26–28th, 30th, 32nd, 34th, 36th, and 37th week of gestation | After intervention (at birth) for group comparison | Birth weight | grams | 3076.8±311.2 | 3125.5±287.4‡ | ||
Apgar score, 1st minute | ≤7; n (%) | 2 (6.1) | 5 (15.2) ‡ | ||||||||
8–10; n (%) | 31 (93.9) | 28 (84.8) ‡ | |||||||||
Apgar score, 5th minutes | ≤7; n (%) | 0 | 0 ‡ | ||||||||
8–10; n (%) | 33 (100) | 33 (100) ‡ | |||||||||
Length of labour, Minute | First stage | 520 ± 19 | 660 ± 27* | ||||||||
Second stage | 27 ± 15 | 31 ± 14‡ | |||||||||
Total labour | 559 ± 20 | 684 ± 28* | |||||||||
4. Chang MY, et al. 2008 | EG: 116 CG: 120 |
Taiwan | RCT | Music Therapy provided daily for 2 weeks | Pre/post difference for group comparison | Stress: PSS, points | Pretest | 17·4 ±4·6 | 16·7 ±4·3 | ||
Posttest | 15.3 ± 5.2 | 15.8 ± 6.0 | |||||||||
Pre-post diff. | -2.1 | -0.9* | |||||||||
Anxiety: S-STAI, points | Pretest | 37·9 ±9·8 | 37·1±10·0 | ||||||||
Posttest | 35.8 ± 10.9 | 37.8 ± 12.1 | |||||||||
Pre-post diff | -2.1 | 0.7* | |||||||||
Depression -Edinburg postnatal depression scale (EPDS), points | Pretest | 12·1±3·5 | 12·2±3·9 | ||||||||
Posttest | 10.3 ± 4.1 | 12.1 ± 4.6 | |||||||||
Pre-post diff. | 1.8 | 0.1* | |||||||||
5. Satyapriya M, et al. 2009 | EG:45 CG:45 |
India | RCT | Yoga daily in the 2nd and 3rd trimester | Pre/post difference for groups comparison | Stress: PSS points, group difference | 20th week of pregnancy | 15.9 ± 5.0 | 15.4±5.7‡ | ||
36th week of pregnancy | 10.9 ± 4.9 | 17.3±5.3* | |||||||||
Pre-post diff | 5.0 | -1.9* | |||||||||
6. Yang M, et al. 2009 | EG:60 CG:60 |
China | RCT | Music therapy for 30 minutes on 3 consecutive days at admission for expected preterm birth | Pre/post difference for group comparison | Anxiety: STAI points, mean for pre/post and mean and SD for the pre/post difference reported | Pretest | 40.7 | 41.9‡ | ||
Posttest | 26.6 | 41.8* | |||||||||
Pre-post diff. | -14.1±5.8 | -0.1±2.8* | |||||||||
7. Urech C, et al. 2010 | EG1: 13 EG2: 13 CG:13 |
Switzerland | RCT | Progressive Muscle relaxation and Guided imaginary experiment applied for 10 minutes only | Pre/post | State anxiety: S-STAI | Groups did not differ significantly in change of state anxiety from pre to post intervention. Anxiety decreased equally in all three groups from pre- to post-relaxation,F(1,35) = 5.14, p = .030*, d = .38 | ||||
8. Liu YH, et al. 2010 | EG:30 CG:30 |
Taiwan | RCT | Music therapy for 1 hour during labour | Posttest for group comparison | Labour anxiety using Visual Analogue Scale (VAS-A), points | Latent phase | 6.4 ± 3.0 | 5.2 ± 2.2‡ | ||
Active phase | 8.2 ± 2.3 | 7.7 ± 2.1‡ | |||||||||
Latent and active phase diff. | -1.8 | 2.5* | |||||||||
9. Simavli S, et al. 2014 | EG:67 CG:65 |
Turkey | RCT | Music therapy during labour | Pre/post for group comparison | Labour anxiety: VAS-A, points | Pretest | 2.8±0.4 | 2.7±0.4‡ | ||
Latent phase | 4.3 ± 0.8 | 5.1 ± 0.9* | |||||||||
Active phase | 8.47 ± 0.7 | 9.4 ± 0.7* | |||||||||
Second phase | 9.1 ± 0.6 | 9.8 ± 0.4* | |||||||||
2 h after delivery | 1.7± 0.3 | 4.2 ± 0.8* | |||||||||
Birth weight | G | 3375 ± 245 | 3420 ± 239‡ | ||||||||
Apgar 9/10 | n (%) | 67 (100%) | 61 (93.8%) + | ||||||||
Duration of labour, Minutes | Latent phase | 162 ± 15 | 164 ± 15‡ | ||||||||
Active phase | 189 ± 28 | 198 ± 15* | |||||||||
Second phase | 83 ± 13 | 89 ± 18* | |||||||||
Third stage | 17 ± 50 | 17 ± 5‡ | |||||||||
Mode of delivery; n (%) χ2 test, P>0.05 |
Caesarian section | 5 (6.9) | 9 (12.2) ‡ | ||||||||
Instrumental | 2(2.7) | 5 (6.8) ‡ | |||||||||
Spontaneous vaginal delivery | 65 (90.2) | 60 (81.0) ‡ | |||||||||
Episiotomy | 51 (76.1) | 52 (80.0) ‡ | |||||||||
Latent phase labour | SBP, mm Hg | 106.0±13.1 | 110.2±9.3* | ||||||||
DBP, mmHg | 66.3±4.9 | 68.3±3.8* | |||||||||
Hear rate | 76.0±4.8 | 78.7±5.9* | |||||||||
Active phase labour | SBP, mm Hg | 99.7±12.3 | 108.3±10.6* | ||||||||
DBP, mmHg | 62.7±5.1 | 68.3±3.8* | |||||||||
Hear rate | 74.4±4.9 | 78.7±5.8* | |||||||||
Second stage labour | SBP, mm Hg | 91.6±16.1 | 101.1±9.1* | ||||||||
DBP, mmHg | 60.6±2.4 | 59.9±11.5‡ | |||||||||
Hear rate | 73.9±3.8 | 76.5±3.7* | |||||||||
2 h postpartum period | SBP, mm Hg | 94.2±5.0 | 99.9±15.5* | ||||||||
DBP, mmHg | 59.4±2.4 | 63.4±10.7* | |||||||||
Hear rate | 72.1±3.9 | 75.4±10.4* | |||||||||
10. Simavli S, et al. 2014 | EG:71 CG:70 |
Turkey | RCT | Music therapy during labour | Posttest group comparison | Antenatal depression: EPDS | Mean (SD) score | 8.0 (2.8) | 8.5 (2.6) ‡ | ||
EPDS≥10, n (%) | 18 (25.4) | 21 (30.0) ‡ | |||||||||
EPDS≥13, n (%) | 8 (11.3) | 9 (12.9) ‡ | |||||||||
Postnatal depression day 1 | Mean (SD) score | 7.3±2.4 | 8.3±2.8* | ||||||||
EPDS≥10, n (%) | 11 (15.5) | 22 (31.4)* | |||||||||
EPDS≥13, n (%) | 4 (5.6) | 12 (17.1)* | |||||||||
Postnatal depression: EPDS, day 8 | EPDS, points | 7.1±2.1 | 8.6±2.9* | ||||||||
EPDS≥10, n (%) | 9 (12.7) | 25 (35.7)* | |||||||||
EPDS≥13, n (%) | 4 (5.6) | 13 (18.6)* | |||||||||
Postnatal Anxiety: VAS-A | VAS-A (1 h) | 3.3±0.5 | 4.9±0.9* | ||||||||
VAS-A (4 h) | 2.7±0.4 | 4.2±0.8* | |||||||||
VAS-A (8 h) | 2.3±0.3 | 3.3±0.5* | |||||||||
VAS-A (16 h) | 1.7±0.3 | 2.8±0.4* | |||||||||
VAS-A (24 h) | 0.9±0.6 | 2.3±0.3* | |||||||||
11. Tragea C, et al. 2014 | EG:31 CG:29 |
Greece | RCT | Breathing and progressive muscle relaxation 1–2 times a day for 6 weeks | Pre/post difference for group comparison | Stress: PSS, points | Pre-post diff. | −3.7±1.8 | −0.5±1.8* | ||
Anxiety: S-STAI | Pre-post diff. | -3.5±2.8 | -2.0±2.9 ‡ | ||||||||
Anxiety: T-STAI | Pre-post diff. | -3.8 (1.4) | -1.6 (2.5) ‡ | ||||||||
12. Guardino CM, et al. 2014 | EG:24 CG:23 |
USA | RCT | Mindfulness training | Pre/post (immediate posttest and 6 weeks after post test | PSS, points: Significant main effect of time: p < 0.05* | Pretest | 41.8±6.0 | 39.9±8.6‡ | ||
Posttest immediate | 37.3±5.4 | 35.8±8.0‡ | |||||||||
Posttest 6 weeks | 36.2±5.9 | 37.4±7.3‡ | |||||||||
Anxiety: S-STAI: Significant main effect of time: p = 0.001* | Pretest | 45.7±7.6 | 44.4±11.0‡ | ||||||||
Posttest immediate | 39.7±6.3 | 37.4±11.5‡ | |||||||||
Posttest 6 weeks | 38.1±8.8 | 36.2±10.8‡ | |||||||||
13. Newham J, et al. 2014 | EG:29 CG:22 |
UK | RCT | Yoga training and practice applied for 8 weeks | Pre/post difference for group comparison | Anxiety: S-STAI, Points, medians (IQR) | Baseline | 28(24–42) | 32 (24–37) | ||
End line | 27(22–36) | 34 (25–38) ‡ | |||||||||
Anxiety: T-STAI, Points, medians (IQR) | Baseline: | 34 (29–40) | 35 (33–39) | ||||||||
End line: | 34 (29–39 | 34 (30–41) ‡ | |||||||||
Depression: EPDS, Points, medians (IQR) | Baseline: | 5 (2–10) | 5 (4–8) | ||||||||
End line: | 4 (2–7) | 6 (3–10)* | |||||||||
Anxiety: WDEQ | Baseline: | 74 (62–87 | 77 (60–85) | ||||||||
End line: | 61 (42–77) | 69 (58–78)* | |||||||||
14. Davis K, et al. 2015 | EG:23 CG:23 |
USA | RCT | Yoga for 8 weeks | Pre/post, and midline assessment | Depression: EPDS, points | Baseline | 10.1 ± 4.5 | 10.6±5.1 | ||
Midline | 8.5 ± 4.9 | 8.8 ±6.0 | |||||||||
End line | 6.4 ± 4.0 | 7.3 ± 5.1 | |||||||||
Baseline-end line mean diff. | 3.7 | 3.3‡ | |||||||||
Anxiety: S-STAI), points | Baseline | 36.9 ±12.2 | 41.7±10.8 | ||||||||
Midline | 41.8±15.2 | 39.0±11.4 | |||||||||
End line | 34.8±10.7 | 38.8 ±13.7 | |||||||||
Baseline-end line mean diff. | 2.1 | 2.9‡ | |||||||||
Anxiety: T-STAI, points | Baseline | 45.0 ±12.1 | 45.4 ±10.2 | ||||||||
Midline | 43.1 ±11.4 | 42.4±13.5 | |||||||||
End line | 38.4 ±9.9 | 40.4±10.9 | |||||||||
Baseline-end line mean diff. | 6.6 | 5‡ | |||||||||
15. Chang HC, et al. 2015 | EG: 145 CG: 151 |
Taiwan | RCT | Music therapy during 2nd and / or 3rd trimester | Pre/post for pre-post mean difference for group comparison | Stress: PSS, points | Pretest | 16.5±4.9 | 16.4±4.8 | ||
Posttest | 16.0 ±5.6 | 16.4 ±5.3 | |||||||||
Pre-post diff. | 0.5 | 0‡ | |||||||||
STRESS: Pregnancy Stress Rating Scale (PSRS) | Pretest | 53.7±24.1 | 49.9±22.3 | ||||||||
Posttest | 54.0±23.6 | 54.9±22.7 | |||||||||
Pre-post diff. | 0.3 | 4.8* | |||||||||
16. Liu YH, et al. 2016 | EG:61 CG:60 |
Taiwan | RCT | Music therapy for 2 weeks | Pre/post | Stress: PSS, points | Pretest: | 17.1 ± 5.4 | 16.3 ± 5.2 | ||
Posttest: | 17.9 ± 4.1 | 19.3 ± 2.5 | |||||||||
Pre-pots mean diff. for group comparison | -0.8 | -3.0* | |||||||||
Anxiety: S-STAI, points | Pretest | 39.7 ± 10.7 | 40.2 ± 10.2 | ||||||||
Posttest | 37.3±10.0 | 42.1±11.6 | |||||||||
Pre-pots mean diff. group comparison | 2.4 | -1.9* | |||||||||
17. Muthukrishnan S, et al. 2016 | EG:37 CG:37 |
India | RCT | Mindfulness Meditation for 4 weeks from 13–16 gestational week | 5 weeks after enrollment (at 17–18 weeks of gestation) | Stress: PSS, points | Posttest between group comparison | 19.1±1.4 | 32.1±2.40* | ||
BP: mmHg | SBP | 109.22±3.8 | 124.68±5.6* | ||||||||
DBP | 69.11±2.23 | 69.11±2.2‡ | |||||||||
Hear rate variability | Beats/min | 26.59±2.1 | 20.65±1.5* | ||||||||
Respiratory rate | Breath/minute | 18.08 ±1.8 | 19.27±2.1* | ||||||||
Cold Pressor systolic blood pressure response. | 9.68±1.8 | 13.38±2.23* | |||||||||
Cold Pressor diastolic blood pressure response. | 4.19±0.98 | 7.54±1.4* | |||||||||
Mental arithmetic systolic blood pressure response. | 8.97±2.21 | 13.49±3.1* | |||||||||
Mental arithmetic diastolic blood pressure response. | 5.22±1.53 | 4.38±1.32 + | |||||||||
18. Beevi Z, et al. 2016 | EG:28 CG:28 |
Malaysia | Quasi-experimental | Hypnosis practiced since 16 week of gestation | Pre/post: | Stress: DASS-21, points at 36 weeks of gestation | Posttest mean group difference (raw data not given) | 5.8 ±5.4 | 10.7 ±8.9* | ||
F (1,44) = 4.70, p = 0.03, partial ŋ2 = .101* | |||||||||||
Anxiety: DASS-21, points at 36 weeks of gestation | Posttest mean group difference (raw data not given) | F(1,44) = 10.76,p = 0.01, partial ŋ2 = 0.20* | |||||||||
Depression: DASS-21, points at 36 weeks of gestation | Posttest mean group difference | F(1,16) = 0.958,p = 0.342, partial ŋ2 = .06. ‡ | |||||||||
19. Beevi Z, et al. 2017 | EG: 23 CG: 22 |
Malaysia | Quasi-experimental | Hypnosis provided at 16, 20, 28, and 36 weeks of their pregnancy and advised to practice every day until labour | Posttest / done at birth | Birth weight, g | 3103.5±301.2 | 3070.9±367.24 ‡ | |||
SVD, n (%) | 19 (42.2) | 14 (31.1) ‡ | |||||||||
C/S, n (%) | 4 (8.9) | 8 (17.8) ‡ | |||||||||
Apgar score at 1 minute, % | 5 | 0 | 4.3‡ | ||||||||
6 | 0 | 4.3‡ | |||||||||
8 | 4.3 | 18.2‡ | |||||||||
9 | 95.7 | 72.7 * | |||||||||
Apgar score at 5 minute | 9 | 0 | 4.5‡ | ||||||||
10 | 100 | 95.5‡ | |||||||||
20. Gonzalezet al. 2017 | EG: 204 CG: 205 |
Spain | RCT | Music therapy for 40 minutes daily for 2 weeks | Posttest for group comparison | Birth weight | Kg | 3.4±0.4 | 3.4±0.5 ‡ | ||
Newborn length | Cm | 50.3±1.86 | 50.6±2.0 ‡ | ||||||||
head circumference | Cm | 34.5±1.3 | 34.6±1.4 ‡ | ||||||||
Apgar score | 1 minute, | 9.1±0.8) | 9.0±0.9 ‡ | ||||||||
Apgar score | 5 minute, | 9.9±0.3 | 9.9±0.4 ‡ | ||||||||
21. Novelia S, et al. 2018 | EG:15 CG:15 |
Indonesia | Quasi experimental | Yoga 2 times in 2 weeks each lasting 90 minutes | Posttest group comparison: | Anxiety (Anxiety: Hamilton Anxiety Rating Scale), n (%): (t = -9.83, p = 0.01)* | Yes | 2 (13.3%) | 15 (100%) | ||
No | 13 (86.7%) | 0 (0%) | |||||||||
22. Gonzalez et al. 2018 | EG: 204 CG: 205 |
Spain | RCT | Music therapy for 40 minutes daily for 2 weeks | Posttest group comparison | Onset of labour n (%),p < 0.01* |
Spontaneous | 140 (68.63) | 111 (54.2) | ||
Stimulated | 5 (2.5) | 12 (5.9) | |||||||||
Induced | 59 (28.9) | 82 (40.0) | |||||||||
Mode of delivery; n (%),P = 0.58‡ | Vaginal | 155 (75.9) | 151 (73.7) | ||||||||
C/S, n (%) | 49 (24.02) | 54 (26.3) | |||||||||
Labour duration | First stage, hours | 4.36 ±3.7 | 5.54 ±4.8* | ||||||||
State-Trait-Anxiety (STA); posttest, group comparison | STA, points | 30.6±13.2 | 43.1 ±15.0* | ||||||||
23. Beevi Z, et al. 2019 | EG:28 CG:28 |
Malaysia | Quasi-experimental | Hypnosis provided at 16, 20, 28, and 36 weeks of their pregnancy and advised to practice every day until labour | 2 month postnatal mean (SD) difference for group comparison | Stress: DASS-21 | 5.5±5.1 | 3.6±5.1 ‡ | |||
Anxiety: DASS-21 | 2.9±3.0 | 38.4± 58.8* | |||||||||
Depression: DASS-21 | 1.3± 2.4 | 6.7± 5.7* | |||||||||
Depression: EPDS | 5.7±2.8 | 10.6±4.0* | |||||||||
24. Pan Win Lan, et al. 2019 | EG:39 CG:35 |
Taiwan | RCT | Mindfulness based Programs: Once every week for 8 weeks | Baseline and 3mo postpartum, mean (SD) | Stress: PSS, points | Pretest | 15.4(5.7) | 13.8(6.0) | ||
Posttest | 11.6 ± 6.1 | 14.3 ±5.2 | |||||||||
Pre-post diff | 3.8 | 0.5* | |||||||||
Depression: EPDS, points | Pretest | 9.5±4.0 | 8.7±4.5 | ||||||||
Posttest | 6.5 ± 4.5 | 8.8 ±3.4 | |||||||||
Pre-post diff | 3 | -0.1* | |||||||||
25. Ahmadi M, et al. 2019 | EG:75 CG:75 |
Iran | RCT | Progressive muscle relaxation/PMR | Posttest between group comparison | Length at birth | CM | 52.1±3.6 | 48.6±3.4* | ||
Birth weight | G | 3400±0.5 | 3200±0.6* | ||||||||
Postpartum depression, day 1 | Zung’s Self-rating Depression Scale | 56.5±0.5 | 57.1±0.6‡ | ||||||||
Postpartum depression, day 3 | Zung’s Self-rating Depression Scale | 49.7±0.4 | 59.4±0.7* | ||||||||
Postpartum depression, day 10 | Zung’s Self-rating Depression Scale | 44±0.4 | 60.3±0.8* | ||||||||
26. Rajeswari S, et al. 2020 | EG: 120 CG: 119 |
India | RCT | Progressive Muscle Relaxation daily practice from 21/22 weeks of gestation until delivery | Posttest group comparison | Stress: Calvin Hobel scale: P < 0.001* |
Minimal; n (%) | 0 (0.00) | 0 (0.0) | ||
Mild; n (%) | 51 (41.6) | 19 (15.2) | |||||||||
Moderate; n (%) | 67 (54.4) | 71 (56.8) | |||||||||
Severe; n (%) | 5 (4.00) | 35 (28.0) | |||||||||
Overall stress; | 40.5 ±8.6 | 77.6 ±8.9* | |||||||||
Anxiety (S-STAI) Fisher exact test: F3 = 17.80, P < 0.001* |
Minimal; n (%) | 0 (0.0) | 0 (0.0) | ||||||||
Mild; n (%) | 22 (17.9) | 9 (7.2) | |||||||||
Moderate; n (%) | 97 (78.9) | 84 (67.2) | |||||||||
Severe; n (%) | 4(3.2) | 32 (25.6) | |||||||||
Anxiety (T-STAI) Fisher exact test: F3 = 18.60, P < 0.001* |
Minimal; n (%) | 0 (0.00) | 0 (0.0) | ||||||||
Mild; n (%) | 24 (10.0) | 10 (8.0) | |||||||||
Moderate; n (%) | 95 (83.0) | 83 (66.4) | |||||||||
Severe; n (%) | 4 (3.0) | 32 (25.6) | |||||||||
Overall anxiety: (STAI) Fisher exact test: F3 = 19.80, P < 0.001* |
Minimal; n (%) | 0 (0.0) | 0 (0.0) | ||||||||
Mild; n (%) | 26 (11.0) | 11 (8.8) | |||||||||
Moderate; n (%) | 93 (82.0) | 82 (65.6) | |||||||||
Severe; n (%) | 4 (32.0) | 32 (25.6) | |||||||||
Postpartum depression | EPDS, points | 6.9 ± 2.5 | 10.5 ±2.7* | ||||||||
Gestational age, n (%) P = 0.01* |
Before 37 weeks | 14 (11.5) | 25 (20.3) | ||||||||
After 37 weeks | 108 (88.5) | 98 (79.7) | |||||||||
Gestational age (weeks) | 38.0±3.6 | 37.2±4.2* | |||||||||
Apgar score; n (%); fisher exact test: P = 0.06‡ | 0‑3 | 0 (0.0) | 3 (2.4) | ||||||||
4–6 | 2 (1.7) | 10 (8.2) | |||||||||
7–10 | 120 (98.3) | 110 (89.4) | |||||||||
Apgar score | Score/10 | 8.3 ±0.2 | 8.0 ±0.6 ‡ | ||||||||
Birth weight | Kg | 2.7 ±0.4 | 2.6 ±0.5* | ||||||||
Mode of delivery n (%): P = 0.001* |
Normal vaginal | 90.0 (74.2) | 61.0 (49.6) | ||||||||
Assisted vaginal | 5.0 (4.0) | 12.0 (9.8) | |||||||||
C/S | 27 (21.8) | 50 (40.60) | |||||||||
Induced labour P = 0.019* |
Yes, n (%) | 110(9.0) | 23 (20) | ||||||||
No, n (%) | 111 (91.0) | 100 (80.0) | |||||||||
Hypertension P = 0.037* |
Yes, n (%) | 4 (3.0) | 12 (10.0) | ||||||||
No, n (%) | 118 (97) | 111 (90) | |||||||||
27. Zarenejad M, et al. 2020 | EG:30 CG:30 |
Iran | RCT | Mindfulness: 6 group counseling sessions twice a week, and each session lasted for 60 min | Posttest group comparison | Pregnancy-Related Anxiety: Posttest between group difference P = 0.001* |
Pretest, | 182.9 ± 74.2 | 195.1 ± 42.9 | ||
Posttest immediate | 154.5 ± 61.8 | 187.9 ± 41.5 | |||||||||
Posttest 1 month later | 124.9 ± 45.5 | 182.5 ± 41.7 | |||||||||
28. Abd Elgwad FMH, et al. 2021 | EG:40 CG:40 |
Egypt | Non-randomized controlled clinical trial | Benson’s Relaxation twice daily (separated by 3 hours) for 3 days | Posttest group comparison | Stress: PSS, n (%) | Immediate posttest: P = 0.01* | Yes | 25 (62.5) | 40 (100) | |
No | 15 (37.5) | 0 (0) | |||||||||
Posttest after 3 days: P = 0.01* | Yes | 10 (25) | 40 (100) | ||||||||
No | 30 (75) | 0 (0) | |||||||||
Blood pressure: mmHg | SBP: Pretest | 158.3±12.2 | 150.5±18.8* | ||||||||
SBP immediate posttest | 144.1±12.1 | 145.1±17.1‡ | |||||||||
SBP 3 days posttest | 119.3±3.3 | 145.1±17.1* | |||||||||
DBP pretest | 95.2±11.2 | 90.8±12.2* | |||||||||
DBP immediate posttest | 87.8±9.5 | 87.4±9.8‡ | |||||||||
DBP 3 days posttest | 77.0±4.6 | 87.4±9.8* | |||||||||
Heart rate, | Pretest | 92.3±7.2 | 97.8±16.3+ | ||||||||
Immediate posttest | 87.4±6.1 | 93.1±10.0* | |||||||||
3 days posttest | 81.2±3.8 | 93.1±11.0* | |||||||||
Respiration rate | Pretest | 21.45±2.2 | 22.8±2.9* | ||||||||
Immediate posttest | 20.7±1.2 | 22.4±2.7* | |||||||||
3 days posttest | 18.6±1.2 | 22.4±2.7* | |||||||||
29. Bauer I, et al. 2021 | EG1: 12 EG2: 12 CG: 12 |
Germany | RCT (3-arm, parallel-group) |
EG1: Music EG2: Guided imagery (GI) CG: Resting Provided for 20 minute during labour |
Pre/post | Indicators | Music group | GI group | Control group | ||
Cardiovascular activity on heart rate, 5 minutes posttest | −2.33±2.9 | −1.9±1.8 | −2.4±(3.4‡ | ||||||||
Cardiovascular activity on heart rate, 10 minutes posttest | − 2.5±5.6 | −1.4±3.0 | −2.6±4.3‡ | ||||||||
Heart rate variability | No significant group effect, F(2,94) = 0.624, p = .538‡ | ||||||||||
Skin conductance 5 minute posttest | 0.01±0.1 | 0.2± 0.7 | −0.1± 0.5‡ | ||||||||
Skin conductance 10 minute posttest | −0.04±0.2 | −0.7±1.5 | −0.1±0.6‡ | ||||||||
30. Estrella-Juarez F, et al. 2022 | EG1: 104 EG2: 124 CG: 115 |
Spain | RCT 3-arm parallel group |
EG1:Music therapy and EG2: Virtual reality (VR) intervention during labour | Pre/post | Outcomes | Music | VR | Control | ||
First stage of labour, h | 4.7±4.1 | 4.3±3.1 | 6.3±5.2* | ||||||||
Spontaneous labour n (%) | 50 (48.1) | 103 (82.4) | 59±51.8* | ||||||||
Induction labour, n (%) | 54 (51.9) | 22 (17.6) | 55 (48.2)* | ||||||||
SVD, n (%) | 49 (47.1) | 73 (58.4) | 56 (49.1) ‡ | ||||||||
Instrumental assisted, n (%) | 21 (20.2) | 32 (25.6) | 26 (22.8) ‡ | ||||||||
C/S, n (%) | 34 (32.7) | 20 (16) | 32 (28.1) ‡ | ||||||||
Pretest T-STAI | 19.0± 6.9 | 19.2±7.1 | 19.8±7.4 | ||||||||
Posttest T-STAI | 12.6±6.0 | 12.4±5.9 | 19.2±9.0 | ||||||||
Pre-post mean diff. (within group comparison) | 6.4* | 6.8* | 0.6‡ | ||||||||
Pretest S-STAI | 16.3±5.8 | 16.6±6.8 | 16.5±4.8 | ||||||||
Posttest S-STAI | 14.7±3.3 | 15.2±3.3 | 17.6 ±7.2 | ||||||||
Pre-post diff (between group comparison) | 1.6‡ | 1.3 ‡ | −1.1 ‡ | ||||||||
SBP | 106.9±8.3 | 108.3±9.8 | 115.9±11.4* | ||||||||
DBP | 69.9±7.3 | 70.4±7.9 | 75.0±8.9* | ||||||||
Heart rate | 79.2±8.4 | 79.8±7.9 | 83.0±10.4* | ||||||||
31. Abarghoee SN, et al. 2022 | EG1: 35 EG2: 35 CG:35 |
Iran | RCT (A parallel, three-armed) |
Benson Relaxation Technique (BRT) and Music Therapy (MT) | Pre/post within and between group comparison | Anxiety: S-STAI; Pre-post difference within group comparison | BRT group | MT group | CG | ||
Pre: 50.6±1.3 | 49.4±1.6 | 50.3±1.4 | |||||||||
Post: 42.3±1.3 | 43.1±1.2 | 48.3±1.7 | |||||||||
diff: 8.3* | diff: 6.3* | diff: 2.0‡ | |||||||||
Anxiety (S-STAI) pre/post between group comparison | Pre: 50.6±1.3 | 49.4±1.6 | 50.3±1.4 ‡ | ||||||||
Post: 42.3±1.3 | 43.1±1.2 | 48.3±1.7* | |||||||||
32. Ghorbanneja d S, et al. 2022 | EG: 44 CG: 44 |
Iran | RCT | Jacobson’s progressive muscle relaxation | Posttest between group comparison | Birth weight | G | 2863.5±176.0 | 2762.7±202.1* | ||
Birth length | CM | 47.8±2.1 | 47.5±2.2‡ | ||||||||
HC | CM | 34.7±0.2 | 34.5 0.1‡ | ||||||||
Gestational age | Week | 36.3±0.7 | 36.2±0.8‡ | ||||||||
Apgar score | 1st min | 9.0±0.4 | 8.8±0.3‡ | ||||||||
BP: mmHg | SBP | 137.6±3.9 | 147.5±5.0* | ||||||||
DBP | 88.7±3.8 | 99.2±4.5* | |||||||||
FBS | Mg/Dl | 101.8±6.8 | 111.0±9.5* |
Abbreviations: ACTH, Adrenocorticotropic hormone; BP, Blood pressure; CG, CM, Centimeter; Control group; C/S: Cesarean section; DASS-21, Depression, anxiety, stress scale- 21 items version; DBP, Diastolic blood pressure; EG, Experimental group; EPDS, Edinburgh postnatal depression scale; FBS, Fasting blood glucose; h, hour; HR, Heart rate; GI, Guided imaginary; IQR, Inter-quartile range; Kg, Kilogram; mg/dL, milligram per deciliter; Mo, Month; PSS, Perceived stress scale; Pre, pretest, post, posttest, diff, difference; RCT, Randomized control trial; SBP, Systolic blood pressure; SD, Standard deviation; S-STAI-S, State-trait anxiety inventory–state version; T-STAI, State-trait anxiety inventory–trait version; SVD, Spontaneous vaginal delivery; VAS, Visual analogue scale; WDEQ, Wijma delivery expectancy questionnaire–modified version.
Note
* P < 0.05
+ p = 0.05
‡ P ≥ 0.05