TABLE 1.
Patients | Case 1 | Case 2 | Case 3 |
---|---|---|---|
Sex | Male | Male | Male |
Calculated MELD | 32 | 11 | 42 |
Procedure | Heart transplant and liver transplant | Heart transplant and liver transplant | CABG and liver transplant |
Transplant date | January 29, 2023 | October 19, 2022 | May 8, 2023 |
Age at transplant, y | 58 | 54 | 63 |
Donor organ type | DBD | DBD | DBD |
Machine perfusion start | January 28, 2023 20:25 | October 19, 2022 8:25 | May 8, 2023 5:37 |
Machine perfusion end | January 29, 2023 1:56 | October 19, 2022 16:27 | May 8, 2023 13:02 |
Total pump time (h) | 5.52 | 8.03 | 7.42 |
Share distance (NM) | 198 | 458 | 257 |
UNOS “CIT” (h) | 8.77 | 8.72 | 9.25 |
Recipient WIT (h) | 0.43 | 0.37 | 0.5 |
Total liver preservation time (h) | 9.2 | 9.08 | 9.75 |
Actual CIT (h) | 3.25 | 0.69 | 1.83 |
Final hepatic artery flow on pump (L/min) | 0.58 | 0.79 | 0.53 |
Total OR time (h) | 11.6 | 10.6 | 8.7 |
Intraoperative RBC (units) | 9 | 5 | 15 |
Intraoperative FFP (units) | 5 | 3 | 13 |
Intraoperative PLTs (units) | 8 | 1 | 4 |
Intraoperative cryo (units) | 0 | 2 | 2 |
INR post 7 d | 1.3 | 1.1 | 0.9 |
Bilirubin post 7 d (mg/dL) | 0.7 | 0.6 | 1.2 |
Cr at 48 h post (mg/dL) | 1.26 | 0.84 | 2.03 |
Discharged | February 24, 2023 | November 9, 2022 | May 24, 2023 |
CABG, coronary artery bypass graft; CHLT, combined heart-liver transplantation; Cr, creatinine; cryo, cryoprecipitate; DBD, donation after brain death; FFP, fresh–frozen plasma; INR, international normalization ratio; MELD, model for end-stage liver disease; NM, nautical miles; OR, operative time; PLT, platelets; RBC, red blood cells; UNOS “CIT”, United Network of Organ Sharing cold ischemia time (defined as donor cross clamp until recipient recirculation); WIT, warm ischemia time.