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. 2023 Dec 4;13(1):2290838. doi: 10.1080/22221751.2023.2290838

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 6. — Lung pathological changes and viral load of mice challenged with pH1N1. (A) The mice were intranasally challenged with 10 LD₅₀ of pH1N1 at 6 weeks post-immunization. On day 5 post infection (DPI), all mice were sacrificed, and the lungs were collected, which were used for (B) H&E staining, (C) pathology score evaluation, and (D) viral copies detection. Data were shown as the mean ± SD. Statistical significance was determined using one-way ANOVA. ns, no significance; *, P < 0.05; **, P < 0.01; ***, P < 0.001.