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. 2023 Aug 25;78(1):154–163. doi: 10.1093/cid/ciad501

Table 2.

Effectiveness of Community-based Screening for Tuberculosis Using Low-Complexity Screening Tests per 100 000 People Screened

Median Number of DALYs Averted Through Community-Based Screening [95% UR]
Scenario Country Median Number of Xpert Tests Completed [95% UR] Median Number of People With TB Treated [95% UR] Absolute Relative to Xpert for All
No active case-finding—Scenario 1 All countries 0 [0, 0] 0 [0, 0] 0 [0, 0]
CRP—Scenario 2 India 14 000 [11000, 18 000] 430 [350, 520] 930 [720, 1200] 56%
Philippines 15 000 [12000, 19 000] 1600 [1300, 2000] 3400 [2600, 4300] 56%
South Africa 15 000 [11000, 19 000] 1200 [930, 1500] 2500 [1900, 3300] 56%
Uganda 14 000 [11000, 18 000] 560 [430, 720] 1200 [860, 1600] 56%
Vietnam 14 000 [11000, 18 000] 450 [360, 570] 950 [710, 1300] 56%
Mean 15 000 [11000, 19 000] 850 [670, 1100] 1800 [1400, 2300] 56%
Hypothetical Screening test—Scenario 3a India 27 000 [23000, 31 000] 630 [550, 720] 1400 [1100, 1700] 83%
Philippines 28 000 [24000, 33 000] 2400 [2100, 2700] 5100 [4100, 6100] 83%
South Africa 28 000 [24000, 32 000] 1800 [1500, 2100] 3700 [2900, 4700] 83%
Uganda 27 000 [23000, 31 000] 820 [660, 1000] 1700 [1300, 2200] 83%
Vietnam 27 000 [23000, 31 000] 670 [560, 800] 1400 [1100, 1800] 83%
Mean 27 000 [23000, 32 000] 1300 [1100, 1500] 2700 [2100, 3300] 83%
Hypothetical Screening test—Scenario 3b India 27 000 [23000, 31 000] 630 [550, 720] 1400 [1100, 1700] 83%
Philippines 28 000 [24000, 32 000] 2400 [2100, 2800] 5100 [4100, 6200] 82%
South Africa 28 000 [24000, 32 000] 1800 [1500, 2100] 3700 [2900, 4700] 83%
Uganda 27 000 [23000, 31 000] 830 [660, 1000] 1800 [1300, 2200] 83%
Vietnam 27 000 [23000, 31 000] 670 [560, 800] 1400 [1100, 1800] 83%
Mean 27 000 [23000, 32 000] 1300 [1100, 1500] 2700 [2100, 3300] 83%
Hypothetical Screening test—Scenario 3c India 5100 [4300, 6100] 630 [550, 720] 1400 [1100, 1700] 83%
Philippines 6900 [6000, 8000] 2400 [2100, 2800] 5100 [4100, 6100] 83%
South Africa 6200 [5300, 7300] 1700 [1500, 2100] 3700 [2900, 4600] 82%
Uganda 5300 [4400, 6300] 820 [660, 1000] 1700 [1300, 2200] 83%
Vietnam 5100 [4300, 6100] 670 [560, 790] 1400 [1100, 1800] 83%
Mean 5700 [4800, 6800] 1300 [1100, 1500] 2700 [2100, 3300] 83%
Xpert for all—Scenario 4 India 100 000 760 [700, 840] 1700 [1400, 2000]
Philippines 100 000 2900 [2600, 3200] 6100 [5100, 7200]
South Africa 100 000 2100 [1800, 2400] 4500 [3600, 5500]
Uganda 100 000 1000 [820, 1200] 2100 [1600, 2600]
Vietnam 100 000 810 [700, 940] 1700 [1400, 2100]
Mean 100 000 1500 [1300, 1700] 3200 [2600, 3900]

Figures in bold represent the mean value across all five countries analysed.

Abbreviations: CRP, C-reactive protein; DALY, disability adjusted life year; TB, tuberculosis; UR, uncertainty range.