Table 2.
Median Number of DALYs Averted Through Community-Based Screening [95% UR] | |||||
---|---|---|---|---|---|
Scenario | Country | Median Number of Xpert Tests Completed [95% UR] | Median Number of People With TB Treated [95% UR] | Absolute | Relative to Xpert for All |
No active case-finding—Scenario 1 | All countries | 0 [0, 0] | 0 [0, 0] | 0 [0, 0] | – |
CRP—Scenario 2 | India | 14 000 [11000, 18 000] | 430 [350, 520] | 930 [720, 1200] | 56% |
Philippines | 15 000 [12000, 19 000] | 1600 [1300, 2000] | 3400 [2600, 4300] | 56% | |
South Africa | 15 000 [11000, 19 000] | 1200 [930, 1500] | 2500 [1900, 3300] | 56% | |
Uganda | 14 000 [11000, 18 000] | 560 [430, 720] | 1200 [860, 1600] | 56% | |
Vietnam | 14 000 [11000, 18 000] | 450 [360, 570] | 950 [710, 1300] | 56% | |
Mean | 15 000 [11000, 19 000] | 850 [670, 1100] | 1800 [1400, 2300] | 56% | |
Hypothetical Screening test—Scenario 3a | India | 27 000 [23000, 31 000] | 630 [550, 720] | 1400 [1100, 1700] | 83% |
Philippines | 28 000 [24000, 33 000] | 2400 [2100, 2700] | 5100 [4100, 6100] | 83% | |
South Africa | 28 000 [24000, 32 000] | 1800 [1500, 2100] | 3700 [2900, 4700] | 83% | |
Uganda | 27 000 [23000, 31 000] | 820 [660, 1000] | 1700 [1300, 2200] | 83% | |
Vietnam | 27 000 [23000, 31 000] | 670 [560, 800] | 1400 [1100, 1800] | 83% | |
Mean | 27 000 [23000, 32 000] | 1300 [1100, 1500] | 2700 [2100, 3300] | 83% | |
Hypothetical Screening test—Scenario 3b | India | 27 000 [23000, 31 000] | 630 [550, 720] | 1400 [1100, 1700] | 83% |
Philippines | 28 000 [24000, 32 000] | 2400 [2100, 2800] | 5100 [4100, 6200] | 82% | |
South Africa | 28 000 [24000, 32 000] | 1800 [1500, 2100] | 3700 [2900, 4700] | 83% | |
Uganda | 27 000 [23000, 31 000] | 830 [660, 1000] | 1800 [1300, 2200] | 83% | |
Vietnam | 27 000 [23000, 31 000] | 670 [560, 800] | 1400 [1100, 1800] | 83% | |
Mean | 27 000 [23000, 32 000] | 1300 [1100, 1500] | 2700 [2100, 3300] | 83% | |
Hypothetical Screening test—Scenario 3c | India | 5100 [4300, 6100] | 630 [550, 720] | 1400 [1100, 1700] | 83% |
Philippines | 6900 [6000, 8000] | 2400 [2100, 2800] | 5100 [4100, 6100] | 83% | |
South Africa | 6200 [5300, 7300] | 1700 [1500, 2100] | 3700 [2900, 4600] | 82% | |
Uganda | 5300 [4400, 6300] | 820 [660, 1000] | 1700 [1300, 2200] | 83% | |
Vietnam | 5100 [4300, 6100] | 670 [560, 790] | 1400 [1100, 1800] | 83% | |
Mean | 5700 [4800, 6800] | 1300 [1100, 1500] | 2700 [2100, 3300] | 83% | |
Xpert for all—Scenario 4 | India | 100 000 | 760 [700, 840] | 1700 [1400, 2000] | – |
Philippines | 100 000 | 2900 [2600, 3200] | 6100 [5100, 7200] | – | |
South Africa | 100 000 | 2100 [1800, 2400] | 4500 [3600, 5500] | – | |
Uganda | 100 000 | 1000 [820, 1200] | 2100 [1600, 2600] | – | |
Vietnam | 100 000 | 810 [700, 940] | 1700 [1400, 2100] | – | |
Mean | 100 000 | 1500 [1300, 1700] | 3200 [2600, 3900] | – |
Figures in bold represent the mean value across all five countries analysed.
Abbreviations: CRP, C-reactive protein; DALY, disability adjusted life year; TB, tuberculosis; UR, uncertainty range.