Table 1.
Demographic Characteristics and Comorbid Conditions in Patients With Klebsiella pneumoniae Bloodstream Infections
| Characteristic or Condition | Patients, No. (%)a | ||
|---|---|---|---|
| Total Cohort (N = 562) | Prospective Cohort (n = 108) | Retrospective Cohort (n = 454) | |
| Male sex | 335 (59.6) | 68 (63) | 267 (58.8) |
| Age, mean (SD), y | 62.1 (16.8) | 62.9 (19.7) | 61.9 (16.0) |
| BMI, mean (SD)b | 26.9 (7.3) | 26.7 (7.2) | 26.9 (7.3) |
| Polymicrobial bacteremiac | 140 (24.9) | 29 (26.9) | 111 (24.4) |
| Immunosuppressed | 284 (50.5) | 51 (47.2) | 233 (51.3) |
| CCI, mean (SD) | 5.37 (2.9) | 5.21 (3.15) | 5.41 (2.9) |
| Comorbid conditionsd | |||
| Cancer | 178 (31.7) | 32 (29.6) | 146 (32.2) |
| Diabetes | 182 (32.4) | 32 (29.6) | 150 (33.0) |
| Coronary artery disease | 109 (19.4) | 24 (22.2) | 85 (18.7) |
| COPD or asthma | 90 (16.0) | 17 (15.7) | 73 (16.1) |
| Liver disease | 94 (16.7) | 16 (14.8) | 78 (17.2) |
| Chronic kidney disease | 145 (25.8) | 31 (28.7) | 114 (25.1) |
| ICU admission | 207 (36.8) | 39 (36.1) | 168 (37.0) |
| Hospital death | 81 (14.4) | 11 (10.2) | 70 (15.4) |
Abbreviations: BMI, body mass index; CCI, Charlson comorbidity index; COPD, chronic obstructive lung disease; ICU, intensive care unit, SD, standard deviation.
aData represent no. (%) of patients unless otherwise specified.
bBMI calculated as weight in kilograms divided by height in meters squared.
cSee Supplementary Figure 1 for further details.
dThe 6 most common comorbid conditions are listed.