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. 2024 Jan 12;15:1320546. doi: 10.3389/fpsyt.2024.1320546

Table 3.

Comorbidities and gender.

Authors Study design States Sample characteristics Outcomes
Banzhaf et al. (2012) (49) Cross sectional Germany N = 171 BPD patients
♀ 114
♂ 57
  • Bulimia nervosa: 19.3% ♀ vs. 5.36% ♂

  • Binge eating disorder: 0.87% ♀ vs. 7.14% ♂

  • Panic with agoraphobia: 9.6% ♀ vs. 3.6% ♂

  • PTSD: 35.96% ♀ vs. 14.29% ♂

  • Antisocial personality disorder: 10.53% ♀ vs. 32.14% ♂

  • Narcissistic personality disorder 2.63% ♀ vs. 20.45% ♂

Barrachina et al. (2011) (57) Cross sectional Spain N = 484 BPD patients
♀ 402
♂ 82
  • Antisocial personality disorder: 8.2% ♀ vs. 22% ♂

  • Dependent personality disorder 2.4% ♀ vs. 17.2% ♂

Dehlbom et al. (2022) (56) Cross sectional Sweden N = 5,530 BPD patients
♀ 4,728
♂ 802
  • Antisocial personality disorder: 1.1% ♀ vs. 6.7% ♂

  • PTSD 16.5% ♀ vs. 11.2% ♂

  • Eating disorder: 15.1% ♀ vs. 3.1% ♂

  • Substance use disorders: 34.2% ♀ vs. 49.3% ♂

  • Nonaffective psychosis: 5.9% ♀ vs. 10.7% ♂

Grant et al. (2008) (16) Epidemiologic survey
Second wave of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)
United States N = 34,653 subjects;
♀ 6.2%
♂ 5.6%
  • Major depressive disorder 36.1% ♀ vs. 27.2%♂

  • Dysthymia 11.9% ♀ vs. 7.1%♂

  • Any substance use disorder 66.2%♀ vs. 80.9% ♂

  • Panic with agoraphobia 9.6% ♀ vs. 3.6% ♂

  • Specific phobia 31.7% ♀ vs. 16.2% ♂

  • Generalized anxiety 26.4% ♀ vs. 18.7% ♂

  • PTSD 38.2% ♀ vs. 23.6% ♂

  • Antisocial personality disorder: 9% ♀ vs. 19.4% ♂

  • Narcissistic personality disorder 32.2% ♀ vs. 47.0% ♂

Johnson et al. (2003) (13) Cross sectional United States N = 668 PD patients;
among them 240 BPD patients
♀ 175
♂ 65
  • Substance use disorders: 58.3% ♀ vs. 84.6% ♂

  • PTSD: 50.9% ♀ vs. 30.8% ♂

  • Eating disorder: 41.7% ♀ vs. 18.5% ♂

  • Narcissistic personality disorder 4.6% ♀ vs. 21.9% ♂

  • Antisocial personality disorder: 10.3% ♀ vs. 29.7% ♂

  • Schizotypal personality disorder: 10.3% ♀ vs. 24.6% ♂

McCormick (2007) (4) Cross sectional United States N = 163 BPD patients
♀ 138
♂ 25
  • Antisocial personality disorder: 21% ♀ vs. 40% ♂

  • Generalized anxiety disorder: 55% ♀ vs. 32% ♂

  • Any somatoform disorder: 14% ♀ vs. 0% ♂

  • Histrionic personality disorder: 25% ♀ vs. 0% ♂

Sher et al. (2019) (8) Case–Control study United States N = 348 BPD patients
♀ 203
♂145
N = 163 HC
♀82
♂ 81
  • Narcissistic personality disorder 36% ♀ vs. 64.1% ♂

  • Antisocial personality disorder: 16.7% ♀ vs. 55.2% ♂

  • Schizotypal personality disorder: 21.7% ♀ vs. 34.5% ♂

  • Paranoid personality disorder: 30.5% ♀ vs. 49.7% ♂

  • Alcohol and substance use disorders: 36.9% ♀ vs. 53.1% ♂

  • Dependent personality disorder: 25.6% ♀ vs. 15.9% ♂

  • Obsessive-compulsive personality disorders: 60.1% ♀ vs. 46.9% ♂

Tadić et al. (2009) (6) Cross sectional Germany N = 159 BPD patients
♀ 110
♂ 49
  • Substance use disorders: 67.3% ♀ vs. 83.7% ♂

  • Alcohol dependency 42.7% ♀ vs. 65.3% ♂

  • Affective disorder: 94% ♀ vs. 82% ♂

  • Anxiety disorder: 92% ♀ vs. 80% ♂

  • Eating disorder: 35% ♀ vs. 18% ♂

  • Anorexia nervosa: 21% ♀ vs. 4% ♂

Zanarini et al. (1998a) (54) Cross sectional United States N = 504 patients;
N = 379 with BPD diagnosis
♀ 296
♂ 83
N = 125 other PD diagnosis
♀ 70
♂ 55
  • Substance abuse:

  • alcohol abuse/dependence: 46% ♀ vs. 74% ♂

  • drug abuse/dependence: 41% ♀ vs. 65% ♂

  • overall substance abuse/dependence: 59% ♀ vs. 82% ♂

  • ED:

  • anorexia nervosa: 25% ♀ vs. 7% ♂

  • bulimia nervosa: 30% ♀ vs. 10% ♂

  • eating disorder not otherwise specified: 30% ♀ vs. 11% ♂

  • overall eating disorder category: 62% ♀ vs. 21% ♂

  • PTSD: 61% ♀ vs. 35% ♂

Zanarini et al. (1998b) (55) Cross sectional United States N = 504 patients;
N = 379 with BPD diagnosis
♀ 296
♂ 83
N = 125 other PD diagnosis
♀ 70
♂ 55
  • Narcissistic personality disorder 13% ♀ vs. 30% ♂

  • Antisocial personality disorder: 16% ♀ vs. 48% ♂

  • Paranoid personality disorder: 26% ♀ vs. 45% ♂

  • Passive-aggressive personality disorder: 19% ♀ vs. 46% ♂

  • Sadistic personality disorder 3% ♀ vs. 16% ♂

  • Cluster:

  • odd cluster disorder: 27% ♀ vs. 47% ♂

  • dramatic cluster disorder: 32% ♀ vs. 68% ♂

Zlotnick et al. (2002) (12) Cross sectional United States N = 1,500 outpatients;
N = 149 BPD patients
♀ 105
♂ 44
  • Eating disorder: 29.5% ♀ vs. 13.6% ♂

  • Substance use disorder: 38.1% ♀ vs. 63.6% ♂

  • Antisocial personality disorder 11.4% ♀ vs. 38.6% ♂

BPD, borderline personality disorder; HC, Healthy Controls; PTSD, Post-Traumatic Stress Disorder; ED, Eating Disorders; ♂, men; ♀, women.