TABLE 4.
Relative abundance of the cervical microbiome in various reproductive conditions.
| Reproductive condition | Author (Year) | Genital microbiome relative abundance (%) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Actinobacteria | Bacteroidetes | Chlamydiae | Cyanobacteria | Firmicutes | Fusobacteria | Proteobacteria | Tenericutes | ||
| Chlamydia trachomatis | Di Pietro (2018) [21] | Gardnerella 14 | Prevotella 6 | Lactobacillus 50 | Leptotrichia 21 | ||||
| Filardo (2019) [56] | Gardnerella 15.5 | Prevotella 6.5 | Lactobacillus 51.1 | ||||||
| Aerococcus 1 | |||||||||
| Asymptomatic Chlamydia trachomatis | Filardo (2017) [20] | Gardnerella 14.3 | Prevotella 0.5 | Chlamydia | Lactobacillus 60 | Leptotrichia 10 | Escherichia | Ureaplasma | |
| Atopobium | Megasphera | Fusobacterium | Mycoplasma | ||||||
| 10 Bifidobacterium | Dialister | ||||||||
| Streptococcus | |||||||||
| Aerococcus | |||||||||
| Parvimonas | |||||||||
| HPV/CT | Di Pietro (2018) [21] | Gardnerella 19 | Bacteroidetes a <1 | Firmicutes a 63 | Fusobacteria a <1 | ||||
| Atopobium 4 | |||||||||
| HPV | Di Pietro (2018) [21] | Actinobacteria a 1.3 | Bacteroidetes a <1 | Firmicutes a 98 | Fusobacteria a <1 | Proteobacteria a <1 | Tenericutes a <1 | ||
| HPV infection - LSIL | Kwasniewski (2018) [57] | Actinobacteria a 1 | Bacilli a 84 | Gammproteobacteria a 8.2 | |||||
| Clostridia a 0.1 | |||||||||
| HPV infection—HSIL | Kwasniewski (2018) [57] | Actinobacteria a 8.1 | Nostocophycideae a 0.15 | Bacilli a 27.69 | Gammproteobacteria a 61.48 | ||||
| Clostridia a 0.2 | Alphaproteobacteria a 0.41 | ||||||||
| Infectious infertility | Graspeuntner (2018) [22] | Gardnerella 10.08 | Prevotella 7.37 | Lactobacillus 57.74 | Sneathia 2.58 | Enterobacteriaceae, unclassified a 0.27 | Mycoplasma 1.71 | ||
| Atopobium 2.18 | Porphyromonas 0.27 | Streptococcus 5.5 | |||||||
| Corynebacterium 1.28 | Lachnospiraceae a 1.69 | ||||||||
| Bifidobacterium 0.18 | Veillonella 1.63 | ||||||||
| Dialister 1.25 | |||||||||
| Aerococcus 0.48 | |||||||||
| Non-infectious infertility | Graspeuntner (2018) [22] | Gardnerella 5.61 | Prevotella 3.93 | Lactobacillus 69.01 | Sneathia 0.5 | Enterobacteriaceae, unclassified a 0.98 | Mycoplasma 0.02 | ||
| Atopobium 2.72 | Lachnospiraceae a 6.59 | ||||||||
| Bifidobacterium 0.21 | Aerococcus 1.49 | ||||||||
| Dialister 0.94 | |||||||||
| Veillonella 0.76 | |||||||||
| Streptococcus 0.65 | |||||||||
| Clostridiales, unclassified a 0.37 | |||||||||
| Stage 3 endometriosis | Cregger (2017) [11] | Barnesiella 19.75 | Clostridium XIVa 2.25 | Sneathia 0.25 | Achromobacter 0.75 | ||||
| Bacteroides 1.75 | Staphylococcus 1.5 | ||||||||
| Tannerella 1.75 | Coprococcus 1.25 | ||||||||
| Parabacteroides 1.25 | Propionibacterium 1.25 | ||||||||
| Alkalitalea 0.75 | Allobaculum 1 | ||||||||
| Butyricicoccus 1 | |||||||||
| Acetivibrio 0.75 | |||||||||
| Anaerotruncus 0.75 | |||||||||
| Ruminococcus 0.75 | |||||||||
| Turicibacter 0.75 | |||||||||
| Coprobacillus 0.5 | |||||||||
| Lactobacillus 0.5 | |||||||||
| Clostridium XIVb 0.25 | |||||||||
| Flavonifractor 0.25 | |||||||||
| Endometriosis—other stages | Cregger (2017) [11] | Barnesiella 0.93 | |||||||
| Stage 3–4 endometriosis | Ata (2019) [23] | 2 Gardnerella | 3 Prevotella | Lactobacillus | |||||
| 5 Atopobium | Dialister | ||||||||
| Streptococcus | |||||||||
| PCOS | Tu (2020) [25] | Gardnerella | Prevotella | Lactobacillus | Sneathia | Escherichia-Shigella | Ureaplasma | ||
| Atopobium | Porphyromonas | Streptococcus | Fusobacterium | Campylobacter | Mycoplasma | ||||
| Bifidobacteriu | Finegoldia | Acinetobacter | |||||||
| Varibaculum | Peptoniphilus | Sutterella | |||||||
| Corynebacterium | Aerococcus | ||||||||
| Dialister | |||||||||
| Megasphaera | |||||||||
| Anaerococcus | |||||||||
| Veillonella | |||||||||
| Peptostreptococcus | |||||||||
| Staphylococcus | |||||||||
a
Unknown genera.