Table 2.

Findings of each study included

ID	QIDS mean change (SE)	HAM-D mean change (SE)	BDI mean change (SE)	MADRS mean change (SE)	Side effects recorded
A1	Baseline to 6 weeks post = −8.0 (1.0)	Baseline to 6 weeks post = −10.5 (1.0)		Baseline to 6 weeks = −14 (1.7)	Headache (n = 12), nausea (n = 4)
A2	Baseline to 5 weeks post = −11.0 (1.62) Baseline to 8 weeks post = −10.7 (1.41)	Baseline to 5 weeks post = −14.9 (2.2) Baseline to 8 weeks post = −14.4 (1.9)	(BDI-II) Baseline to 5 weeks post = −23.7 (3.14) Baseline to 8 weeks post = −23.7 (2.75)	N/A	Mild to moderate headache
A3	Baseline to: 1 week = −11.8 (1.53), 2 weeks = −12.9 (1.45), 3 weeks = −12.8 (1.58), 5 weeks = −11.0 (1.66), 3 months = −9.2 (1.83)	Baseline to 1 week post = −14.0 (2.4)	Baseline to 1 week post = −25.0 (3.18) Baseline to 3 months post = −18.5 (3.78)	N/A	Mild anxiety (n = 12), confusion (n = 9), mild nausea (n = 4), transient headache (n = 4), mild transient paranoia (n = 1)
A4	N/A	N/A	Baseline to 1 week post = −22.2 (3.18)	N/A	None recorded
A5	Baseline to 5 weeks = −8.0 (1.42)	N/A	N/A	N/A	None recorded
A6.a	N/A	N/A	N/A	Baseline to 3 weeks post = −12.0 (1.3)	Headache, nausea, and/ or dizziness (n = 179)
A6.b	N/A	N/A	N/A	Baseline to 3 weeks post = −7.9 (1.4)	See A6.a
A6.c	N/A	N/A	N/A	Baseline to 3 weeks post = −5.4 (1.4)	See A6.a

QIDS, Quick Inventory of Depressive Symptomatology; HAM-D, Hamilton Depression Rating Scale; BDI, Beck Depression Inventory; MADRS, Montgomery–Åsberg Depression Rating Scale; SE, standard error; N/A, not available.