Figure 5.
Transfection of SK-N-AS cells with ASOs directed against SCN1A-dsAS. Treatment with ASO3 showed a significant increase in SCN1A mRNA expression by about 15-fold (a, ***p < 0.001) and reduction in SCN1A-dsAS expression by about 40% compared to control and mock transfected cells (b, *p < 0.05).