Table 4.
Detailed summary of individual patient specifications
| Patient ID | Sex | Age at surgery (years) | Seizure manifestation (years) | Epilepsy duration (years) | Seizure frequency | Number of previous ASMs | ASMs at surgery | Type of surgery/resection | Investigated tissue | Pathology |
|---|---|---|---|---|---|---|---|---|---|---|
| SKV-13 | M | 13.3 | 0.3 | 12.9 | Daily | 2 | 1 | Temporal lobe resection, amygdalohippocampectomy, anterior insular, frontal opercular, and basal cortex | Anterior temporal lobe | HS, FCD IIIa |
| SKV-04 | W | 4.2 | 0.2 | 4.0 | Daily | 12 | 2 | Subtotal frontal and anterior insular resection | Frontal lobe | MOGHE |
| SKV-03 | M | 4.8 | 1.4 | 3.4 | Daily | 10 | 2 | Subtotal frontal and anterior insular and anterior cingular resection | Frontal lobe | MOGHE |
| SKV-05 | M | 11.5 | 8.0 | 3.5 | Daily | 1 | 1 | Temporal lobe resection | Anterior temporal lobe | MVNT |
| SKV-08 | W | 8.5 | 5.0 | 3.5 | Weekly | 2 | 1 | Temporal lobe resection | Anterior temporal lobe | GG |
| LMU-16 | W | 6.5 | 5.0 | 1.5 | Weekly | 3 | 1 | Parietal lesionectomy | Parietal lobe | FCD Ia |
| LMU-17 | W | 0.8 | 0.1 | 0.8 | Daily | 4 | 4 | Hemispherotomy | Frontal and parietal lobe, insula | FCD IIb, PMG |
| SKV-01 | W | 1.3 | 0.3 | 1.0 | Weekly | 7 | 4 | Hemispherotomy | Frontal lobe | FCD IIa |
| SKV-06 | W | 7.3 | 2.0 | 5.3 | Daily | 5 | 2 | Hemispherotomy | Frontal lobe | Gliosis |
| SKV-07 | M | 13.2 | 0.5 | 12.7 | Daily | 4 | 2 | Hemispherotomy | Frontal lobe | Gliosis |
| SKV-10 | W | 7.3 | 1.4 | 5.9 | Daily | 4 | 4 | Subtotal frontal lobe resection | Frontal lobe | MOGHE |
| SKV-14 | W | 7.7 | 2.0 | 5.7 | Monthly | 4 | 2 | Temporal lobe resection | Anterior temporal lobe | HS |
| SKV-15 | W | 18.7 | 3.0 | 15.7 | Daily | 3 | 2 | Temporal lobe resection | Anterior temporal lobe | HS |
| SKV-12 | W | 12.1 | 3.5 | 8.6 | Daily | 4 | 2 | Hemispherotomy | Frontal lobe | PMG |
| SKV-02 | W | 12.2 | 0.6 | 11.6 | Daily | 10 | 4 | Hemispherotomy | Frontal lobe | FCD IIId, gliosis |
| SKV-09 | W | 13.9 | 7.2 | 6.8 | Monthly | 5 | 2 | Temporal lobe resection | Temporal lobe | mMCD |
| SVK-11 | W | 16.1 | 5.5 | 10.6 | Month | 3 | 2 | Temporal lobe resection | Anterior temporal lobe | FCD IIa |
| LMU-18 | W | 4.0 | 0.6 | 3.4 | Daily | 6 | 2 | Hemispherotomy | Frontal lobe | MOGHE |
Note: Patients SVK-03 and 13 received ketogenic diet as a presurgical antiseizure treatment. Abbreviations: HS = hippocampal sclerosis, FCD = focal cortical dysplasia, GG = ganglioglioma, MOGHE = mild malformation of cortical development with oligodendroglial hyperplasia, MVNT = multinodular and vacuolating neuronal tumor, mMCD = mild malformation of cortical development with heterotopic neurons in the white matter, PMG = polymicrogyria, ASMs = antiseizure medications.