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. 2024 Jan 24;9(1):e1136. doi: 10.1097/PR9.0000000000001136

Table 11.

Subgroup comparison for short disease duration of ≤5 years.

FMS (n = 33) SFN (n = 32) P
Median pain intensity during interview (NRS) [range] 5.0 [1–9] 4.0 [1–9] n.s.
Median pain intensity after medication (NRS) [range] 2.0 [0–4] 1.0 [0–1] <0.001
Median number of additional symptoms [range] 7.0 [1–28] 4.0 [0–11] <0.001
Median number of pain aggravating factors [range] 2.0 [1–6] 1.0 [0–3] <0.01
Median number of pain relieving factors [range] 2.0 [1–4] 1.0 [0–3] <0.001
Median number of medications [range] 4.0 [1–8] 3.0 [0–10] n.s.
Median number of nonpharmaceutical therapy attempts [range] 3.0 [0–15] 0.0 [0–4] <0.001
Psychotherapy in past 7/33 (21.2%) 0/32 (0%) <0.01
Median IENFD lower leg (fibers/mm) [range] 6.4 [0–14.4] 5.4 [0–11.8] <0.05
Median IENFD upper thigh (fibers/mm) [range] 8.2 [1.3–16.4] 9.8 [1.5–16.5] n.s.

FMS, fibromyalgia syndrome; IENFD, intraepidermal nerve fiber density; NRS, numeric rating scale; n.s., not significant; SFN, small fiber neuropathy.