Scheme 2. Results of Substrate Scope Studies.

Ph₂SiH₂ was used for all HDF reactions and Ph₂Si(Cl)(NR₂) were used for aminodefluorination reactions.

Isolated yield after flash column chromatography shown in parentheses.

Reactions were stirred at 60 °C for 4 days, followed by the remaining period at 80 °C.

Stoichiometric reaction between PⁱPr₃ and 1 in MeCN (other phosphines behave similarly).