Table 3.
Diagnostic performance of each endoscopic modality for diagnosis of H. pylori infection
| Endoscopic technique | Sensitivity (95% CI) |
Specificity (95% CI) |
PPV (95% CI) |
NPV (95% CI) |
Accuracy (95% CI) |
|---|---|---|---|---|---|
|
M-BLI Enlarged or elongated pits with obscure SECNs or dense fine irregular vessels |
95% (83.1–99.4) |
80% (67.7–89.2) |
76% (65.5–84.1) |
96% (86.1–98.9) |
86% (77.6–92.1) |
|
M-NBI Enlarged or elongated pits with obscure SECNs or dense fine irregular vessels |
92.5% (79.6–98.4) |
86.7% (75.4–94.1) |
82.2% (70.7–89.9) |
94.6% (85.3–98.1) |
89% (81.2–94.4) |
|
LCI Comprehensive findings on LCI were the presence of ≥ 1 of 8 endoscopic findings based on Kyoto classification* |
90% (76.3–97.2) |
70% (56.8–81.2) |
66.7% (57.3–74.9) |
91.3% (80.3–96.4) |
78% (68.6–85.7) |
|
WLI Comprehensive findings on WLI were the presence of ≥ 1 of 8 endoscopic findings based on Kyoto classification* |
80% (64.4–91.0) |
71.7% (58.6–82.6) |
65.3% (55.0-74.3) |
84.3% (73.9–91.1) |
75% (65.3–83.1) |
LCI = Linked Color Imaging, M-BLI = Magnifying Blue Light Imaging, M-NBI = Magnifying Narrow Band Imaging, NPV = Negative predictive value, PPV = Positive predictive value, SECNs = Subepithelial capillary networks, WLI = White Light Imaging
*Eight endoscopic findings based on Kyoto classification included diffuse redness, spotty redness, antral nodularity, sticky mucus, enlarged gastric folds, mucosal edema, xanthoma, and hyperplastic polyp