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. 2024 Jan 26;24:19. doi: 10.1186/s40644-024-00658-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Representative PET images (MIP) of MCF7 tumor-bearing mice at 20 min after injection of ⁶⁸ Ga-DOTA-Ava-BBN2 (left) and ^44gSc-DOTA-Ava-BBN2 (right). Corresponding time-activity curves (middle) show the radioactivity levels in the tumor and muscle for both radiopeptides over time as SUV values (mean ± SEM from n = 3 experiments). Representative PET images (MIP) of PC-3 tumor-bearing mice at 60 min after injection of ⁶⁸ Ga-DOTA-Ava-BBN2 (top) and ^44gSc-DOTA-Ava-BBN2 (bottom) under control (right) and blocking conditions (left). Corresponding time-activity curves (middle) show the radioactivity levels in the tumor and muscle for both radiopeptides over time as SUV values (mean ± SEM from n = 3 experiments). With permission, from Ref. [77]