BBN |
pGlu-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
|
IC50 = 1.36 nM (BBN), 1.8 ± 0.2 nM ([Tyr4]BBN), 3.3 ± 0.4 nM ([Lys3]-BBN), 20.8 ± 0.3(Aca-BBN(7–14)) |
No |
[56–58] |
AMBA |
Gly-4-aminobenzoyl-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
|
Kd = 0.7 ± 0.1 nM (111In-DOTA-AMBA) |
No |
[62, 88] |
RM1 |
Gly-4-aminobenzoyl-H–D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2
|
IC50 = 14 ± 3.4 nM ( natIn-DOTA-RM1) Kd = 2.4 ± 0.2 nM (111In-DOTA-RM1) |
No |
[62, 88] |
RM2 |
4-amino-1-carboxymethylpiperidine-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2
|
IC50 = 7.7 ± 3.3 nM (RM2), 9.3 ± 3.3 nM (natIn-DOTA-RM2), Kd = 2.9 ± 0.4 nM (111In-DOTA-RM2) |
Yes |
[63, 88] |
RM26 |
D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2
|
IC50 = 5.5 ± 0.4 nM (natCo-NOTA-PEG3-RM26) |
Yes |
[70, 88] |
JMV5132 |
MPAA-βAla-βAla-[H–D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2] |
IC50 = 6.8 nM (JMV5132), 3.0 nM (natGa-NODA-JMV5132), 10.0 nM (AlnatF-NODA-JMV5132) |
No |
[67] |
JMV4168 |
βAla-βAla-[H–D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2] |
IC50 = 13.2 nM (JMV4168), 3.2 nM (natGa-DOTA-JMV4168) |
No |
[67] |
JMV594 |
H–D-Phe-Gln-Trp-Ala-Val-GlyHis-Sta-Leu-NH2
|
IC50 = 2.2 ± 0.1 nM (JMV594) |
No |
[66] |
SB3 |
p-aminomethylaniline-diglycolicacid-D-Phe-Gln-Trp-Ala-Val-Gly-His-Leu-NHEt |
IC50 = 4.6 ± 0.5 nM (SB3), 1.5 ± 0.3 nM (natGa-DOTA-SB3) |
No |
[69, 88] |