Table 2.
Correlations of FOXP1 expression with the clinicopathological characteristics of ICC
| Clinicopathological characteristics | Case number(n) | FOXP1 | ||
|---|---|---|---|---|
| Positive number (%) | Χ2 | p | ||
| Age (years) | ||||
| ≥ 63 | 31 | 17(54.8) | 0.013 | 0.908 |
| < 63 | 43 | 23(53.5) | ||
| Sex | ||||
| Male | 34 | 21(61.8) | 1.506 | 0.220 |
| Female | 40 | 19(47.5) | ||
| Differentiation | ||||
| Moderately-well | 48 | 31(64.6) | 6.098 | 0.014 |
| Poorly | 26 | 9(34.6) | ||
| Pathogeny | ||||
| Hepatitis | 12 | 7(58.3) | 0.853 | 0.356 |
| Stones | 5 | 3(60.0) | ||
| History of biliary surgery | 4 | 3(75.0) | ||
| Others | 56 | 28(50.0) | ||
| Tumor size (cm) | ||||
| < 5 | 21 | 9(42.9) | 1.480 | 0.224 |
| ≥ 5 | 53 | 31(58.5) | ||
| Lymph node metastasis | ||||
| Yes | 29 | 10(34.5) | 7.355 | 0.007 |
| No | 45 | 30(66.7) | ||
| Invasion | ||||
| YES | 21 | 7(33.3) | 5.069 | 0.024 |
| No | 53 | 33(66.3) | ||
| TNM Stages | ||||
| I-II | 42 | 29(69.0) | 8.792 | 0.003 |
| III | 32 | 11(34.4) | ||
| Star lesion | ||||
| Yes | 28 | 14(50.0) | 0.298 | 0.585 |
| No | 46 | 26(56.5) | ||
| Micronerve infiltration | ||||
| Yes | 14 | 8(57.1) | 0.066 | 0.797 |
| No | 60 | 32(53.3) | ||
| Vessel invasion | ||||
| Yes | 12 | 8(66.7) | 0.917 | 0.338 |
| No | 62 | 32(51.6) | ||