Figure 6.

Diffuse splenomegaly owing to mast cell infiltration in a 15-year-old neutered female domestic shorthair cat. The spleen (arrows) is enlarged and contains multiple, small, poorly defined hypoechoic foci throughout the parenchyma. Additional ultrasonographic findings included hepatomegaly, abdominal lymphadenopathy and a small peritoneal effusion. Mast cell infiltration of the liver and spleen was confirmed following ultrasound-guided fine-needle aspiration of both organs. A video showing multiple splenic masses due to mast cell infiltration is available as supplementary material