TABLE 1.
Baseline patient characteristics
| Characteristica | Clarithromycin group (n = 35) | Placebo group (n = 41) |
|---|---|---|
| Male patients (no. [%]) | 32 (91.4) | 35 (85.3) |
| Mean (SD) age (yr) | 65 (8.6) | 65 (9.3) |
| Mean (SD) wt (kg) | 84 (19.4) | 81 (12.1) |
| Mean (SD) ht (cm) | 170 (20.2) | 174 (9.9) |
| Mean (SD) NYHA score | 3 (0.9) | 3 (0.7) |
| Mean (SD) no. of treatment days | 27 (12.2) | 27 (13.9) |
| Current smoker (no. [%] of patients) | 5 (14.3) | 4 (9.8) |
| Smoker in past (no. [%] of patients) | 27 (77.1) | 31 (75.6) |
| Medical history (no. [%] of patients) | ||
| COPD | 6 (17.1) | 3 (7.3) |
| Diabetes mellitus | ||
| Type I | 2 (5.7) | 1 (2.4) |
| Type II | 4 (11.4) | 8 (19.5) |
| Hypercholesterolaemia | 20 (57.1) | 27 (65.9) |
| Malignancy | 3 (8.6) | 1 (2.4) |
| CVA or TIA | 2 (5.7) | 6 (14.6) |
| Pectoral angina | 33 (94.3) | 40 (97.6) |
| Myocardal infarction | 20 (57.1) | 23 (56.1) |
| Valvular insufficience | 3 (8.6) | 1 (2.4) |
| Hypertension | 18 (51.4) | 25 (61.0) |
| Earlier vascular surgery | 10 (28.6) | 15 (36.6) |
| Family medical history (no. [%] of patients) | ||
| Cardiovascular disease | 29 (82.9) | 31 (75.6) |
| Diabetes mellitus | 7 (20.0) | 6 (14.6) |
| Medication (no. [%] of patients) | ||
| Statins | 21 (60.0) | 27 (65.9) |
| Antihypertensive drugs | 35 (100) | 41 (100) |
a
Baseline patient characteristics were not significantly different between the treatment groups. Abbreviations: NYHA, New York Heart Association; COPD, chronic obstructive pulmonary disease; CVA, classification for angina pectoris; CVA, cerebrovascular accident; TIA, transient ischemic attack.