Table 2.
Admission data and feline aortic thromboembolism (FATE) characteristics in 40 cats enrolled in a prospective, multicenter, blinded, randomized, placebo-controlled study within 6 h of an event
| Variable | Tissue plasminogen activator group (n = 20) | Placebo group (n = 20) | P value |
|---|---|---|---|
| Age (years) | 8.5 ± 3.9 | 10.5 ± 3.4 | 0.10 |
| Body weight (kg) | 5.1 ± 1.1 | 5.1 ± 1.1 | 0.87 |
| Rectal temperature (ºF) | 96.4 ± 2.5 | 96.2 ± 2.6 | 0.81 |
| Affected limb lactate (mmol/l) | 10.9 ± 3.3 | 11.6 ± 3.7 | 0.62 |
| Heart rate (beats/min) | 193 ± 27 | 195 ± 37 | 0.95 |
| Respiratory rate (breaths/min) | 60 (32–120) | 60 (30–140) | 0.39 |
| Clinicopathologic variables | |||
| Sodium (mEq/l) | 152.9 ± 5.1 | 152.4 ± 5.1 | 0.76 |
| Potassium (mEq/l) | 3.9 ± 0.6 | 4.0 ± 0.8 | 0.70 |
| Creatinine (mg/dl) | 1.4 (0.9–2.3) | 1.6 (1.0–3.2) | 0.06 |
| Lactate (mmol/l) | 3.6 ± 1.2 | 3.1 ± 0.9 | 0.24 |
| Packed cell volume (%) | 42 ± 9 | 42 ± 8 | 0.89 |
| Total protein (g/dl) | 7.7 (6.4–10.6) | 8.0 (6.4–10.0) | 0.77 |
| FATE characteristics | |||
| Limb score | 10 (6–11) | 10 (6–10) | 0.31 |
| Cardiogenic FATE (%) | 95 | 90 | 1.00 |
| Congestive heart failure (%) | 85 | 60 | 0.15 |
| FATE to admission time (h) | 2.4 (0.3–5.5) | 2.0 (0.25–5.5) | 0.57 |
| Admission to needle time (h) | 1.2 (0.3–3.7) | 1.3 (0.5–4.5) | 0.91 |
| FATE to needle time (h) | 4.0 ± 1.7 | 3.8 ± 1.2 | 0.63 |