Skip to main content
. 2023 Dec 28;13(1):53. doi: 10.3390/antiox13010053

Figure 2.

Figure 2

Effects of vitamin B12 supplementation on vitellogenin and mitochondrial stress response in CIA. (A) Representative images show that VIT-2::GFP transgenic animals were synchronized at the L4 stage and fed with killed OP50 and DA1877 bacteria with or without caffeine for 24 h at 20 °C. Bar, 50 μm. (B) An experimental scheme for effects of vitamin B12 on CIA. (C) Comparison of the intensity of VIT-2::GFP in OP50- or DA1877-fed CIA with or without B12 supplementation. Bar, 50 μm. (D) Comparison of the intensity of HSP-6::GFP in CIA fed with OP50 or DA1877 with or without vitamin B12, or with high peptone. Heat stress (HS) was used as a positive control. Bar, 25 μm. Data represent mean ± standard deviation. n.s., p > 0.5. ***, p < 0.001. Number of analyzed animals, n ≥ 25 in respective conditions.