Table 3.
Consumption of the top 10 systemic antibiotics in the years highlighted, expressed as DDD per 100 patient-days (DHPD).
| 2010 | 2019 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Group of ATC | Systemic INN * | DDD per 100 Patient-Days |
% | cum ** % | Group of ATC | Systemic INN * | DDD per 100 Patient-Days |
% | cum ** % | |
| 1. | J01CR02 | Co-amoxiclav | 5.1 | 23.3 | 23.3 | J01CR02 | Co-amoxiclav | 4.7 | 20.0 | 20.0 |
| 2. | J01MA02 | Ciprofloxacin | 2.8 | 12.9 | 36.2 | J01DD04 | Ceftriaxone | 3.3 | 14.3 | 34.3 |
| 3. | J01DC02 | Cefuroxime | 2.1 | 9.5 | 45.7 | J01DC02 | Cefuroxime | 2.2 | 9.5 | 43.7 |
| 4. | J01DD04 | Ceftriaxone | 1.6 | 7.2 | 52.9 | J01AA02 | Doxycycline | 2.0 | 8.6 | 52.4 |
| 5. | J01FA09 | Clarithromycin | 1.3 | 6.1 | 59.0 | J01MA02 | Ciprofloxacin | 1.4 | 6.1 | 58.4 |
| 6. | J01MA12 | Levofloxacin | 1.0 | 4.3 | 63.3 | J01FA09 | Clarithromycin | 1.4 | 5.9 | 64.4 |
| 7. | J01FF01 | Clindamycin | 0.9 | 4.0 | 67.3 | J01MA12 | Levofloxacin | 1.0 | 4.1 | 68.5 |
| 8. | J01FA10 | Azithromycin | 0.8 | 3.4 | 70.7 | J01XD01 | Metronidazole | 0.9 | 3.8 | 72.2 |
| 9. | J01EE01 | Sulfamethoxazol-trimethoprim | 0.7 | 3.2 | 73.9 | J01DB04 | Cefazolin | 0.7 | 3.2 | 75.4 |
| 10. | J01MA14 | Moxifloxacin | 0.6 | 2.6 | 76.5 | J01FF01 | Clindamycin | 0.7 | 3.1 | 78.5 |
| Pandemic years | ||||||||||
| 2020 | 2021 | |||||||||
| Group of ATC | Systemic INN * |
DDD per
100 patient-days |
% | cum ** % | Group of ATC | Systemic INN * |
DDD per
100 patient-days |
% | cum ** % | |
| 1. | J01DD04 | Ceftriaxone | 5.9 | 18.2 | 18.2 | J01DD04 | Ceftriaxone | 6.5 | 19.3 | 19.3 |
| 2. | J01CR02 | Co-amoxiclav | 5.1 | 15.9 | 34.1 | J01CR02 | Co-amoxiclav | 5.4 | 15.9 | 35.2 |
| 3. | J01DC02 | Cefuroxime | 2.3 | 7.2 | 41.3 | J01DC02 | Cefuroxime | 2.1 | 6.2 | 41.4 |
| 4. | J01FA10 | Azithromycin | 2.2 | 7.0 | 48.3 | J01XD01 | Metronidazole | 2.0 | 6.1 | 47.5 |
| 5. | J01FA09 | Clarithromycin | 2.0 | 6.4 | 54.6 | J01FA10 | Azithromycin | 2.0 | 6.0 | 53.5 |
| 6. | J01XD01 | Metronidazole | 1.9 | 5.9 | 60.5 | J01AA02 | Doxycycline | 1.8 | 5.2 | 58.7 |
| 7. | J01MA12 | Levofloxacin | 1.5 | 4.8 | 65.3 | J01FA09 | Clarithromycin | 1.7 | 5.0 | 63.7 |
| 8. | J01MA02 | Ciprofloxacin | 1.5 | 4.6 | 69.9 | J01MA12 | Levofloxacin | 1.6 | 4.8 | 68.5 |
| 9. | J01AA02 | Doxycycline | 1.4 | 4.4 | 74.4 | J01MA02 | Ciprofloxacin | 1.3 | 3.8 | 72.3 |
| 10. | J01DH51 | Imipenem + cilastatin |
1.0 | 3.1 | 77.4 | J01DH51 | Imipenem + cilastatin |
1.0 | 3.0 | 75.4 |
* INN: International Nonproprietary Names. ** cum: cumulative.