Table 2. Variables associated with 28-day mortality in septic shock patients.
| Variables | OR (95%CI) | P |
|---|---|---|
| Sex | ||
| Male | Ref | |
| Female | 0.70 (0.39–1.26) | 0.238 |
| Age | 1.03 (1.01–1.04) | 0.005 |
| BMI | 0.97 (0.90–1.03) | 0.304 |
| Hypertension, yes; | 1.30 (0.77–2.20) | 0.334 |
| Chronic lung disease, yes; | 4.31 (1.45–12.87) | 0.009 |
| Diabetes, yes; | 1.53 (0.76–3.09) | 0.230 |
| Chronic kidney disease, yes; | 1.51 (0.44–5.18) | 0.509 |
| Heart disease, yes; | 1.99 (0.86–4.59) | 0.107 |
| Chronic liver disease, yes; | 1.74 (0.49–6.11) | 0.389 |
| Cardiovascular disease, yes; | 2.07 (0.71–6.01) | 0.183 |
| Chronic bronchitis, yes; | 9.25 (0.95–90.27) | 0.056 |
| Malignancy, yes; | 1.74 (0.89–3.41) | 0.105 |
| Coronary artery disease, yes; | 2.68 (0.87–8.24) | 0.085 |
| Dyslipidemia, yes; | 0.00 (0.00-Inf) | 0.987 |
| Atrial fibrillation, yes; | 2.63 (1.04–6.61) | 0.040 |
| Chronic liver disease, yes; | 1.96 (0.88–4.35) | 0.100 |
| COPD, yes; | 1.38 (0.46–4.10) | 0.566 |
| Cerebrovascular disease, yes; | 2.57 (1.43–4.63) | 0.002 |
| Peripheral vascular disease, yes; | – | 0.984 |
| Infection site | ||
| Urinary system | Ref | |
| Bloodstream | – | 0.983 |
| Gastrointestinal tract | – | 0.984 |
| Gallbladder | – | 0.984 |
| Others | – | 0.984 |
| Coma degree | ||
| Normal state | Ref | |
| Mild coma | 1.51 (0.28–8.08) | 0.629 |
| Moderate coma | 1.89 (1.06–3.36) | 0.030 |
| Severe coma | 1.89 (0.67–5.34) | 0.230 |
| SBP | 0.99 (0.98–1.00) | 0.020 |
| DBP | 0.98 (0.97–1.00) | 0.039 |
| Heart rate | 1.01 (1.00–1.02) | 0.046 |
| Respiratory rate | 1.05 (1.00–1.11) | 0.076 |
| Body temperature | 0.94 (0.68–1.30) | 0.693 |
| Urine volume | 1.00 (1.00–1.00) | 0.503 |
| NLR | 1.02 (1.00–1.03) | 0.052 |
| SII | 1.00 (1.00–1.00) | 0.092 |
| Hb | 1.00 (0.99–1.01) | 0.513 |
| RBC | 0.77 (0.56–1.06) | 0.106 |
| PLT | 1.00 (0.99–1.00) | 0.099 |
| HCT | 0.39 (0.02–7.49) | 0.536 |
| ALT | 1.00 (1.00–1.00) | 0.678 |
| AST | 1.00 (1.00–1.00) | 0.231 |
| TBIL | 1.01 (1.00–1.02) | 0.018 |
| ALB | 0.94 (0.90–0.99) | 0.010 |
| BUN | 1.02 (0.99–1.05) | 0.205 |
| Cr | 1.00 (1.00–1.00) | 0.869 |
| UA | 1.00 (1.00–1.00) | 0.598 |
| K | 1.02 (0.71–1.48) | 0.896 |
| Na | 1.04 (1.00–1.09) | 0.046 |
| Cl | 1.05 (1.01–1.10) | 0.014 |
| Ca | 0.86 (0.30–2.44) | 0.780 |
| GLU | 1.03 (0.95–1.11) | 0.485 |
| CRP | 1.01 (1.00–1.01) | <0.001 |
| PCT | 1.01 (1.00–1.02) | 0.114 |
| WBC | 0.98 (0.94–1.02) | 0.311 |
| LAC | 1.14 (1.05–1.23) | 0.001 |
| Blood PH | 0.10 (0.01–1.35) | 0.083 |
| Oxygenation index (PaO2/FiO2) | 0.58 (0.44–0.75) | <0.001 |
| SaO2 | 0.90 (0.84–0.97) | 0.005 |
| APTT | 1.01 (1.00–1.01) | 0.264 |
| TT | 1.00 (0.99–1.01) | 0.599 |
| PT | 1.03 (1.00–1.07) | 0.036 |
| FIB | 1.08 (0.95–1.23) | 0.236 |
| IgG | 0.98 (0.91–1.05) | 0.534 |
| C3 | 0.29 (0.11–0.78) | 0.015 |
| C4 | 1.00 (1.00–1.00) | 0.394 |
| Fluid resuscitation, yes | 0.84 (0.16–4.41) | 0.834 |
| Vasoactive drugs, yes | 1.01 (0.10–9.85) | 0.994 |
| Glucocorticoids, yes | 4.98 (1.73–14.32) | 0.003 |
| Mechanical ventilation, yes | – | 0.980 |
| Hemodialysis, yes | 4.83 (2.76–8.45) | <0.001 |
| Length of ICU stay | 1.00 (1.00–1.00) | 0.342 |
Notes.
- BMI
- body mass index
- COPD
- chronic obstructive pulmonary disease
- SBP
- systolic blood pressure
- DBP
- diastolic blood pressure
- NLR
- neutrophil to lymphocyte ratio
- SII
- systemic immune-inflammation index
- Hb
- hemoglobin
- RBC
- red blood cell
- PLT
- platelet
- HCT
- hematocrit
- ALT
- alanine aminotransferase
- AST
- aspartate aminotransferase
- TBIL
- total bilirubin
- ALB
- albumin
- BUN
- blood urea nitrogen
- Cr
- creatinine
- UA
- uric acid
- GLU
- blood glucose
- CRP
- C-reactive protein
- PCT
- procalcitonin
- WBC
- white blood cell
- LAC
- lactic acid
- SaO2
- blood oxygen saturation
- APTT
- activated partial thromboplastin time
- TT
- thrombin time
- PT
- prothrombin time
- FIB
- fibrinogen
- IgG
- immunoglobulin G
- ICU
- Intensive Care Unit
- OR
- odds ratio
- CI
- confidence interval