Table 3. Performance of the prediction model in the training and testing sets.
| Datasets | AUC | Accuracy | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|
| Our model | ||||||
| Training set | 0.829 (0.768–0.889) | 0.773 (0.710–0.827) | 0.783 (0.719–0.846) | 0.740 (0.618–0.862) | 0.514 (0.398–0.629) | 0.906 (0.858–0.955) |
| Testing set | 0.825 (0.728–0.923) | 0.747 (0.645–0.833) | 0.677 (0.563–0.791) | 0.923 (0.821–1.000) | 0.533 (0.388–0.679) | 0.957 (0.898–1.000) |
| SOFA | ||||||
| Training set | 0.732 (0.649–0.814) | 0.692 (0.625–0.754) | 0.677 (0.605–0.749) | 0.740 (0.618–0.862) | 0.416 (0.313–0.518) | 0.893 (0.839–0.948) |
| Testing set | 0.707 (0.584–0.830) | 0.747 (0.645–0.833) | 0.862 (0.778–0.946) | 0.462 (0.270–0.653) | 0.571 (0.360–0.783) | 0.800 (0.706–0.894) |
| APACHE II | ||||||
| Training set | 0.713 (0.634–0.791) | 0.678 (0.610–0.740) | 0.665 (0.592–0.738) | 0.720 (0.596–0.844) | 0.400 (0.299–0.501) | 0.884 (0.827–0.941) |
| Testing set | 0.718 (0.601–0.835) | 0.670 (0.564–0.765) | 0.631 (0.513–0.748) | 0.769 (0.607–0.931) | 0.455 (0.307–0.602) | 0.872 (0.777–0.968) |
Notes.
- SOFA
- Sepsis Organ Failure Assessment
- APACHE II
- Acute Physiology and Chronic Health Evaluation II
- AUC
- area under the receiver operating characteristic curve
- PPV
- positive predictive value
- NPV
- negative predictive value
Our model: integrated systolic blood pressure, cerebrovascular disease, Na, oxygenation index (PaO2/FiO2), prothrombin time, glucocorticoids, and hemodialysis;
SOFA: a quantitative scoring index that dynamically characterizes sepsis-associated organ dysfunction, encompassing respiratory system, coagulation system, liver function, cardiovascular system, central nervous system, and renal function.
APACHE II: incorporated the age score, acute physiology score, and chronic health status score.