Table 6.
Different organic acids used for the control of Salmonella infection in humans and animals.
Plant | Major Components | Salmonella Serotype | MIC | Activity | References |
---|---|---|---|---|---|
Thymus vulgaris | Thymol (37.5%), p-cymene (14.49%), γ-terpinene (11.15%), linalool (4.71%), and carvacrol (4.62%) | S. Typhimurium ATCC 14028 | 0.25% v/v | The zone of inhibition in the agar-well diffusion assay was found to be 25.5 mm against S. Typhimurium, with complete clearance of the bacteria at MIC 0.25% v/v | [484] |
Origanum vulgare | Thymol- and carvacrol-based EO | S. enteritidis ATCC 13076 | 120 μg/mL (carvacrol), 130 μg/mL (Thymol) | Complete clearance of the bacteria at 120 μg/mL (carvacrol) and 130 μg/mL (Thymol) in vitro | [485] |
Pistacia atlantica subsp. Kurdica | α-Pinene (10.8%) | S. Typhimurium ATCC 14028 | 0.26 mg/mL | Complete clearance of S. Typhimurium was found to be at 0.5 mL/mL with a zone of inhibition of 22 mm | [486] |
Cinnamomum verum | Not identified |
S. enteritidis, S. Typhimurium, S. Heidelberg |
>20 μL/mL | The zone of inhibition of all of the strains was found to be higher than 20 mm on agar well diffusion assay. | [487] |
Citrus medica L. Var. Sarcodactylis | d-Limonene terpinene |
S. Typhimurium | 2.0 mg/mL | The zone of inhibition was found to be 20 mm and the inhibition of biofilm formation was found to be 90%. | [58] |
Ocimum basilicum | linalool, 1,8-cineole, eugenol, α-terpineol, ρ-cymene, and germacrene D | S. Enteritidis | 20 μg/mL | Two log reduction in the number of Salmonella when used in food products, colonization resistance was evident | [488] |
Allium sativum (Garlic) |
diallyl disulfide | S. Typhimurium | MIC/8 (1/512) μg/mL | Inhibition of biofilm formation by 23%, downregulation of virulence genes including invA and sdiA genes | [489] |
Commercially available Essential oils. | Thymol, carvacrol, cinnamaldehyde | S. Enteritidis | 4.6 mg/mL | Complete clearance of illeal and cecal Salmonella in broiler chicken at 10 dpi, improved illeal integrity, gut immunity modulation | [33] |
Aniba rosaeodora | Linaloo |
S. Typhimurium S. Pullorum |
4 mg/mL 8 mg/mL |
In vitro: complete clearance of the bacteria at 4 mg/mL and 8 mg/mL, respectively In vivo: complete clearance and systemic protection in chicks, modulate host inflammatory process |
[490] |
Cymbopogon citrates (Lemongrass) | Neral, Citral, Geranyl acetate | S. Newport | --- | Significant reduction in bacterial population by 1 log CFU/g when co-cultured with S. Newport | [491] |