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. 2005 Mar;43(3):1251–1255. doi: 10.1128/JCM.43.3.1251-1255.2005

TABLE 2.

In vitro susceptibilities of Aspergillus spp. obtained with RPMI-2% glucose medium, an inoculum size of 105 UFC/ml, 48 of incubation, and different Tween 20 concentrations

Species (no. of isolates) Tween concn (%) MIC (μg/ml)
Amphotericin B
Intraconazole
Voriconazole
Terbinafine
Range GMa Range GM Range GM Range GM
A. fumigatus (7) 5 0.50-4.0 1.18 4.0->8.0 8.83 0.25-2.0 1.18 16.0->16.0 27.13
0.5 0.25-2.0 0.69 0.50->8.0 3.28 0.25-4.0 1.22 4.0->16.0 8.27
0.1 0.25-2.0 0.57 0.25->8.0 1.87 0.12-2.0 0.79 2.0->16.0 5.94
A. terreus (7) 5 2.0-8.0 4.56 2.0-8.0 4.88 2.0-8.0 4.56 4.0 4
0.5 2.0-8.0 4.27 0.06-1.0 0.48 1.0-4.0 1.94 0.50-2.0 0.88
0.1 2.0-8.0 3.74 0.25-0.50 0.26 1.0-4.0 1.81 0.25-0.50 0.41
A. flavus (7) 5 1.0->16.0 2.97 2.0-8.0 4.00 1.0-2.0 1.75 1.0-2.0 1.28
0.5 0.50-8.0 1.94 0.50-1.0 0.65 1.0-2.0 1.35 0.12-0.50 0.33
0.1 1.0-8.0 1.70 0.12-0.50 0.35 1.0-4.0 1.26 0.03-0.50 0.14
A. niger (7) 5 0.50-2.0 0.94 1.0->8.0 6.56 0.12-2.0 0.69 1.0-4.0 2.21
0.5 0.25-2.0 0.67 0.12->8.0 1.75 0.12-2.0 0.67 0.25-2.0 0.61
0.1 0.25-2.0 0.77 0.12->8.0 1.34 0.12-2.0 0.69 0.25-1.0 0.41
Total (28) 5 0.50->16.0 1.97 1.0->8.0 5.79 0.12-8.0 1.60 1.0->16.0 4.66
0.5 0.25-8.0 1.40 0.06->8.0 1.58 0.12-4.0 1.21 0.12->16.0 1.15
0.1 0.25-8 1.29 0.12->8 0.69 0.12-4 1.06 0.03->16 0.64
a

GM, geometric mean.