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Effects of oral administration of aspartame on (A) BDNF, (B) COX-2, and (C) PGE2 levels in the rats’ cerebral cortex. Each bar represents mean ± SD; # p < 0.05, ## p < 0.01 when compared with control group by a one-way ANOVA with Bonferroni’s post-test correction. Rat groups: control diet (control), low dose of aspartame (LA), high dose of aspartame (HA).
