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. 2023 Dec 19;13(1):2. doi: 10.3390/antiox13010002

Figure 4.

Figure 4

Effect of oral administration of aspartame on oxidative stress and antioxidant markers in the rats’ cerebral cortex: (A) GPx, (B) 8-OHdG, and (C) thiobarbituric acid reactive substance (MDA) levels in rats’ cerebral cortex in different groups. Each bar represents mean ± SD; # p < 0.05, ## p < 0.01 when compared with control group by a one-way ANOVA with Bonferroni’s post-test correction. Rat groups: control diet (control), low dose of aspartame (LA), high dose of aspartame (HA).