FIG. 3.

Unrooted phylogenetic tree of human poliovirus type 1 genomes constructed by applying the unweighted pair group method with arithmetic mean for clustering to the DiAlign similarity scores computed using DiAlign. The tree was drawn using PHYLIP (http://evolution.genetics.washington.edu/phylip.html). The origin of each isolate is indicated. We were unable to find the collection date of Taiwanese isolates (gi 33331402, gi 33331404, gi 33331406, and gi 33331408) from a human immunodeficiency virus patient specified in the source publication. When the outlier from Byelorussia, collected during the 1960s, is excluded from the calculations for amino acid conservation, 10 protein signatures that are conserved among all the other genomes are identified.