TABLE 1.
Fully informed predicted numbers of nucleotide and protein signatures, and number of sequences required to approximate fully informed predictionsa
| Genome structure | Virus | No. of genomes in target pool | Approx genome length (1,000 bp) | Conserved and unique fraction of target genome with full data set (%) | Fraction conserved and unique X genome length | x | y | t such that 75% quantile is within 20 of x (no. of target genomes) | t such that 75% quantile is within 20 of y (no. of target genomes) |
|---|---|---|---|---|---|---|---|---|---|
| dsDNA virus | Human adenovirus B | 6 | 35 | 67 | 23.8 | 3 | 18 | 3 | 5 |
| Human papillomavirus type 16 | 8 | 8 | 65 | 5.04 | 11 | 37 | 1 | 2 | |
| JC | 210 | 5 | 68 | 3.5 | 1 | 31 | 10 | 1 | |
| Vaccinia | 6 | 194 | 5 | 9.7 | 0 | 52 | 1 | 3 | |
| Variola | 14 | 186 | 5 | 9.3 | <20 | 90 | 1 | 6 | |
| ssDNA virus | Maize streak | 32 | 2.7 | 52 | 1.4 | 0 | 3 | 1 | 5 |
| Retroid virus | Hepatitis B | 379 | 3 | 20 | 0.5 | 0 | 0 | 1 | 1 |
| ssRNA negative-strand nonsegmented virus | Marburg | 6 | 19 | 56 | 15.8 | 0 | 113 | 4 | 6 |
| Ebola Zaire | 5 | 19 | 80 | 10.6 | 167 | 119 | 1 | 1 | |
| Mumps | 13 | 15 | 85 | 12.8 | 4 | 65 | 6 | 9 | |
| Vesicular stomatitis | 4 | 11 | 88 | 9.7 | 2 | 100 | 4 | 4 | |
| ssRNA negative segmented | Lassa virus segment S | 6 | 3.4 | 13 | 0.44 | 0 | 19 | 2 | 2 |
| ssRNA positive-strand nonsegmented virus | FMDV | 19 | 8 | 33 | 2.64 | 0 | 24 | 3 | 14 |
| Human poliovirus | 31 | 7 | 21 | 1.5 | 0 | 0 | 2 | 3 | |
| Human poliovirus 1 | 22 | 7 | 46 | 3.22 | 0 | 0 | 3 | 3 | |
| Plum pox virus | 5 | 10 | 83 | 8.3 | 14 | 138 | 3 | 4 | |
| SARS coronavirus | 40 | 30 | 78 | 23.4 | 100 | 1106 | 1 | >21 | |
| Venezuelan equine encephalitis virus | 18 | 11 | 5 | 0.6 | 0 | 15 | 2 | 8 |
a
x, number of TaqMan DNA signatures with full data set; y, number of protein signatures with full data set; ds, double-stranded; ss, single-stranded.