TABLE 2.
Susceptibilities of 145 S. pneumoniae isolates to 17 antimicrobial agents
| Agent | MIC
|
% of isolates susceptible or resistanta
|
||||
|---|---|---|---|---|---|---|
| Range | 50% | 90% | S | I | R | |
| Penicillin | 0.03-4 | 0.25 | 2 | 39.3 | 37.9 | 23.0 |
| Cefditoren | 0.06-1 | 0.25 | 0.5 | —c | — | — |
| Cefotaxime | 0.06-2 | 0.25 | 1 | 82.1 | 13.8 | 4.1 |
| Cefepime | 0.5-2 | <0.5 | 2 | 54.5 | 37.2 | 8.3 |
| Chloramphenicol | 4-16 | <4 | 8 | 68.3 | 31.7 | — |
| Erythromycin | 0.06-64 | 8 | >64 | 15.2 | 4.1 | 80.7 |
| Clarithromycin | 0.06-64 | 4 | >64 | 20.0 | 7.6 | 72.4 |
| Clindamycin | 0.06-64 | <0.06 | >64 | 50.3 | 0.7 | 49.0 |
| Levofloxacin | 0.25-8 | 1 | 1 | 100 | — | — |
| Meropenem | 0.12-2 | <0.12 | 0.5 | 82.1 | 17.9 | — |
| Rifampin | 1-4 | <1 | — | 100 | — | — |
| Tetracycline | 0.5-4 | >4 | >4 | 12.4 | 1.4 | 86.2 |
| Trim/Stb | 0.5/9.5-4/76 | <0.5/9.5 | 1/19 | 71.7 | 24.8 | 3.5 |
| Vancomycin | 0.12-1 | 0.5 | 0.5 | 100 | — | — |
a
S, susceptible; I, intermediate; R, resistant.
b
Trim/St, trimethoprim and sulfamethoxazole. Ratio of concentrations of trimethoprim and sulfamethoxazole, 1:19.
c
—, no NCCLS breakpoints were available.