TABLE 3.
Detection of HIV LTR and RNase P DNA using DBS from seropositive and seronegative persons residing in the United States
| HIV sero-status (nd) | HIV-1 DNA detectiona
|
CT rangeb
|
||
|---|---|---|---|---|
| No. (%) positive | No. (%) negative | HIV LTR | RNase P | |
| Positive (103) | 101 (98.1) | 2 (1.9) | 28.6-39.95 (36.04 ± 2.06) | 20.55-31.46 (25.99 ± 2.49) |
| Negative (56) | 0 (0) | 56 (100) | NAc | 20.58-28.07 (23.52 ± 2.22) |
Sensitivity, 98.1% (95% CI, 95.5 to 100%); specificity, 100% (95% CI, 99% to 100%).
The CT values of 2 HIV PCR-negative samples were not included in the HIV LTR range, average, and 1-standard-deviation calculations. However, their respective RNase P CT values were included in the RNase P column. Average and one standard deviation are given in parentheses.
NA, not applicable.
No. of samples.