TABLE 2.
Selected VNTR loci on the genome of N. meningitidis
| Locus | Repeated length (bp) | No. of repeat units | Consensus pattern | Locationa | Function | GenBank accession no. |
|---|---|---|---|---|---|---|
| VNTR01 | 7 | 36 | CAAACAA | 657231-657481 | Putative galactosyltransferase-related protein | NC_003112 |
| VNTR02 | 13 | 29 | GGGCTGTAGAGAT | 1131155-1131527 | Unknown | NC_003112 |
| VNTR03 | 15 | 15 | GCTGAAGCTCCTGCT | 1572374-1572592 | Unknown | NC_003112 |
| VNTR04 | 18 | 15 | GGTATTCCTGACGATTCA | 1952031-1952308 | Unknown | NC_003112 |
| VNTR05 | 15 | 13 | TTTTCTGTTTCGCTG | 2158562-2158750 | Major outer membrane protein | NC_003112 |
| VNTR06 | 9 | 9 | GGCAACTTT | 2158511-2158594 | Putative rotamase | NC_003116 |
| VNTR07 | 6 | 5 | TCTTCA | 863508-863539 | ATP-dependent Clp protease | NC_003112 |
| VNTR08 | 9 | 7 | GCCAAAGCT | 285906-285971 | Unknown | NC_003112 |
| VNTR09 | 24 | 4 | GCAAAACAACAGGCGGCGGCATCA | 1902204-1902308 | Putative PilQ protein | NC_003112 |
| VNTR10 | 5 | 16 | TTGGG | 1273590-1273680 | Unknown | NC_003112 |
| VNTR11 | 10 | 3 | TAATCCACTA | 1303221-1303253 | Noncoding region | NC_003112 |
| VNTR12 | 28 | 5 | GGGAATGACGGAATGTTGCGGGAATCAT | 197212-197358 | Noncoding region | NC_003112 |
| VNTR13 | 24 | 4 | TTCGTGGGAATGACGGGATGTAGG | 52222-52319 | Noncoding region | NC_003112 |
| VNTR14 | 19 | 4 | GCGGGAATGACGAAAGGTT | 2095123-2095210 | Unknown | NC_003112 |
| VNTR15 | 5 | 17 | AAGAG | 940260-940343 | Putative opacity protein | NC_003112 |
a
The locations of VNTR loci were based on N. meningitidis MC58, except for VNTR06, which was based on Z2491.