Table 3.
Summary of rates and proportions of major and minor metabolic characteristics of the overall cohort. The prevalence of the major characteristics is calculated for the overall cohort and the prevalence of the minor characteristics for the remaining cohort after application of the major characteristics. Within the two cohorts of major or minor criteria, an individual can fulfill more than one criterion but may only be classified once. Abbreviations: HF hyperferritinemia, FLI fatty liver index, BMI body mass index, T2DM type 2 diabetes mellitus, HOMA homeostasis model assessment, HDL high-density lipoprotein. The p-value indicates significant difference between the non-HF and the HF group at p < 0.05.
| Major Criteria within the Overall Cohort n = 9915 | |||||||
|
Overall Cohort
n = 9915 |
HF All Grades n = 1388 |
Non-HF
n = 8527 |
p-Value | ||||
|
HF 1
n = 1225 |
HF 2
n = 146 |
HF 3
n = 17 |
|||||
| Major criteria | FLI > 60 | 31% n = 3121 |
All grades 57% (n = 792) | 27% (n = 2329) |
<0.001 | ||
| 54% (n = 661) |
79% (n = 115) |
94% (n = 16) |
|||||
| BMI > 30 kg/m2 | 19% n = 1923 |
All grades 31% (n = 433) | 17% (n = 1490) |
<0.001 | |||
| 30% (n = 367) |
40% (n = 59) |
41% (n = 7) |
|||||
| T2DM | 6% n = 593 |
All grades 10% (n = 140) | 5% (n = 453) |
<0.001 | |||
| 9% (n = 109) |
18% (n = 26) |
29% (n = 5) |
|||||
| Minor Criteria within the Remaining Cohort n = 6436 | |||||||
|
Remaining cohort
n = 6436 |
Remaining HF all grades n = 555 |
Remaining non-HF
n = 5881 |
p-value | ||||
|
HF 1
n = 525 |
HF 2
n = 29 |
HF 3
n = 1 |
|||||
| Minor criteria | Overweight | 43% n = 2758 |
All grades 57% (n = 315) | 42% n = 2443 |
<0.001 | ||
| 55% n = 303 |
2% n = 11 |
100% n = 1 |
|||||
| Arterial hypertension | 44% n = 2813 |
All grades 52% (n = 291) | 43% n = 2522 |
<0.001 | |||
| 49% n = 272 |
3% n = 19 |
0% n = 0 |
|||||
| Elevated HOMA Index | 13% n = 805 |
All grades 21% (n = 114) | 12% n = 691 |
<0.001 | |||
| 19% n = 108 |
1% n = 6 |
0% n = 0 |
|||||
| Impaired fasting glucose | 14% n = 876 |
All grades 23% (n = 126) | 13% n = 750 |
<0.001 | |||
| 22% n = 121 |
1% n = 5 |
0% n = 0 |
|||||
| Low HDL cholesterol | 11% n = 729 |
All grades 14% (n = 77) | 11% n = 652 |
0.048 | |||
| 13% n = 70 |
1% n = 7 |
0% n = 0 |
|||||
| Elevated triglycerides | 8% n = 544 |
All grades 11% (n = 60) | 8% n = 484 |
0.037 | |||
| 11% n = 59 |
1% n = 5 |
0% n = 0 |
|||||