Figure 8.

Pedigrees of the two LRRK2 G2019S-PD patients. (A) Pedigree of Patient1 (donor of iPSC line Mut1) and (B) Pedigree of Patient2 (donor of iPSC line Mut2). Symbols: square, male; circle, female; dot inside circle, mutation carrier; black-colored circles, clinically diagnosed with PD; oblique line, deceased; black arrow, individuals assessed by genetic testing. For each assessed individual, year of birth and LRRK2 status are specified. For each individual diagnosed with PD, aao indicates the age at onset and, if applicable, aad indicates the age at death.