Table 1.

Antioxidant materials employed for wound healing diseases.

Category	Material	Load	Model	Properties	Ref.
Hydrogels	Chitosan, heparin and poly(γ-glutamic acid)	SOD	Diabetic rat model	Accelerating re-epithelialization and collagen deposition	[61]
	Poly(N-isopropyl-acrylamide)/poly(γ-glutamic acid)	SOD	Diabetic rat model	Antioxidant activity and high wound closure rate	[62]
	GelMA with dopamine motifs	Cerium oxide NPs and AMP	Rats	(ROS) scavenging and antibacterial properties	[65]
	SBMA, CBMA and HEMA	Cerium oxide and microRNA-146	Mice	Accelerating wound healing	[66]
	Chitosan-PEG	Silver NPs	Diabetic rabbits	Antioxidant and antibacterial activity	[67]
	Chitosan	Eugenol	-	Antioxidant activity	[71]
	Chitosan-g-polyaniline and benzaldehyde	PEG-co-poly(glycerol sebacate)	Mice	Good self-healing, electro-activity and free radical scavenging capacity	[72]
	Carboxybetaine dextran and sulphobetaine dextran	-	Mice	Self-healing, antioxidative and antifouling properties	[73]
	Alginate	Edudragit NPs and Edavarone	Mice	Wound healing promoting and efficient free radical scavenging	[74]
	Polyvinyl alcohol	Mupirocin and GM-CSF	Diabetic mice	Antibacterial activity and wound closure promoting	[75]
	Silk fibroin	Melanin and berberine	Diabetic rat	Re-epithelialization and wound repair promoting	[76]
Inorganic NPs	Prussian Blue NPs	-	Mice	Antioxidant and collagen deposition	[64]
Liposomal particles	Lecithin nano-liposol	astaxanthin	NIH/3T3 cells	ROS scavenging and antioxidant capacity	[77]
Polymeric matrix	Cellulose	Nanochitosan dust	Human gingival cells	Antioxidant and antimicrobial activity	[70]
	PLA	Asiatic acid	Diabetic mouse model	Accelerating re-epithelization, angiogenesis and ECM formation	[79]
	Poly(L-Lactic-co-caprolactone) (PLCL)	EGCG	Rat liver trauma model	Promoting wound healing and tissue organization	[81]