Figure 8.

US-mediated ROS generation for synergistic anticancer therapy combined with sonodynamic ROS-mediated therapy with accelerated release of immunotherapeutic agents (Reprinted with permission from ref. [130] under the terms of the Creative Commons CC BY license. Copyright 2022, Springer Nature). (a) Schematic illustration of the release of NLG919 and anti−PD−L1 antibody from sonosensitizer−loaded US−responsive nanoparticle. (b) Mechanism of US-mediated anticancer therapy under US irradiation with US−responsive nanoparticles.