Table 1.

‘Regenerative’ anemias that do not always play by the rules

Disease*	Breed association	Cats reported with non-regenerative anemia
Porphyria	Siamese, domestic shorthair	Case reports39,40
Erythrocyte osmotic fragility	Abyssinian, Somali, domestic shorthair, others	41% 41
Pyruvate kinase deficiency	Abyssinian, 42 Somali, 42 Bengal, 43 Egyptian Mau, 43 LaPerm, 43 Maine Coon, 43 Norwegian Forest Cat, 43 Savannah, 43 Siberian, 43 Singapura 43	11% 42
Hemotrophic mycoplasmas	None reported	Up to 50% 20
Immune-mediated hemolytic anemia	None reported	57% 44
Propylthiouracil-induced hemolytic anemia	None reported	66% 3

^*While typically associated with regenerative anemia, these diseases may cause a non-regenerative anemia in a proportion of cases