Table 4.
Abnormality | Possible locations | Possible causes | Image | Description of image |
Erythrophagocytosis | Bone marrow, spleen, lymph node, liver | • Immune-mediated hemolytic anemia
5
• Histiocytic disorder63,70,71 • Multiple myeloma72,73 • Lymphoma58,74 • Acute myeloblastic leukemia 75 • Leishmaniosis 21 |
Erythrophagocytosis in the spleen of an anemic cat. Courtesy of Andrea Siegel | |
Increased numbers of mast cells | Bone marrow, spleen | • Mast cell neoplasia
• Histiocytic disorder 71 Leukemia 75 |
Aspiration cytology of a splenic mast cell tumor. Courtesy of Andrea Siegel | |
Monomorphic population of lymphoid cells | Bone marrow, spleen, lymph node, other organs | • Lymphoma | Renal aspiration showing large granular lymphoma. Courtesy of Andrea Siegel | |
Fungal organisms | Bone marrow, spleen, lymph node, other organs | • Systemic fungal infection | Transthoracic pulmonary aspiration cytology showing Cryptococcus organisms. Courtesy of Andrea Siegel | |
Mycobacterium species | Bone marrow, spleen, lymph node, other organs | • Systemic mycobacterial infection25,26 | Aspiration cytology of mesenteric lymph nodes containing Mycobacterium species. Reproduced from JFMS 2011; 13: 125–128, with permission of Delphine Rivière | |
Myelodysplasia | Bone marrow | • Primary myelodysplastic syndromes
• Secondary myelodysplasia from drug reaction or radiation therapy |
Bone marrow cytology showing a dysplastic, binucleate prorubricyte. Courtesy of Andrea Siegel |