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Inhibition of AIM2 prevents the high-protein diet (HPD)-induced caspase-1 activation. (A) Representative Western blots of caspase-1 and quantification of precursor caspase-1 (Pro-Casp1) and cleaved caspase-1 (p20). (B,C) Serum levels of IL-1β. (B) and IL-18 (C) * p < 0.05, p-values determined by ordinary one-way ANOVA with Sidak’s multiple comparisons test in (A) and Kruskal–Wallis with Dunn’s multiple comparisons test in (B).
