Table 4.
Clinicopathological results of the cats included in the positive Leishmania (PL) and negative Leishmania (NL) groups
| Variables | NL group (n = 106) |
PL group (n = 19) |
RI | P value |
|---|---|---|---|---|
| Haematology | ||||
| RBCs (cells/mm3) | 7,449,505 ± 2,268,986 | 7,473,333 ± 2,055,798 | 7,000,000–11,000,000 | 0.962 |
| WBCs (cells/mm3) | 10,200 (950–77,480) | 10,545 ± 4196 | 4800–14,930 | 0.705 |
| Hb (fl) | 11 ± 3 | 11 (7–15) | 10–16 | 0.879 |
| Hct (g%) | 32 ± 10 | 35 (32–44) | 32–48 | 0.982 |
| MCV (fl) | 43 (33–57) | 44 ± 4 | 36–55 | 0.810 |
| MCH (pg) | 14.7 (10.8–19.7) | 14.7 ± 1.6 | 12.3–16.2 | 0.672 |
| MCHC (g%) | 34 (32–47) | 34 ± 1 | 31–36 | 0.259 |
| MPV (fl) | 17 (9–32) | 18 ± 5 | 8–26 | 0.727 |
| RDW (%) | 15 (12.7–27.1) | 15.37 ± 1.84 | 13.17–17 | 0.781 |
| Platelets (cells/mm3) | 217,000 (1000–644,000) | 252,278 ± 148,735 | 150,000–500,000 | 0.609 |
| Reticulocytes (cells/mm3) | 33,000 (2200–162,100) | 28,078 ± 14,184 | 0–80,000 | 0.106 |
| Neutrophils (cells/mm3) | 7110 (390–76,050) | 7943 ± 4176 | 1600–10,000 | 0.807 |
| Monocytes (cells/mm3) | 230 (30–7670) | 255 (60–920) | 0–650 | 0.940 |
| Lymphocytes (cells/mm3) | 1560 (40–17,270) | 1817 ± 821 | 900–5600 | 0.750 |
| Basophils (cells/mm3) | 10 (0–900) | 10 (0–40) | 0–60 | 0.096 |
| Eosinophils (cells/mm3) | 290 (0–2430) | 499 ± 400 | 60–1470 | 0.439 |
| Serum chemistry | ||||
| ALT (U/l) | 64 (3–743) | 60 ± 38 | 20–72 | 0.060 |
| AST (U/l) | 39 (16–828) | 29 (16–115) | 9–40 | 0.050 |
| ALP (U/l) | 25 (5–97,772) | 15 (4–133) | 0–140 | 0.009 |
| GGT (U/l) | 0.1 (0–5.2) | 0.1 (0–1.4) | 0–4 | 0.256 |
| Total bilirubin (mg/dl) | 0.18 (0.01–20.85) | 0.2 (0.04–3.23) | 0–0.3 | 0.544 |
| Cholesterol (mg/dl) | 160 ± 53 | 151 (72–325) | 64–229 | 0.775 |
| Glucose (mg/dl) | 127 (57–591) | 121 ± 34 | 63–148 | 0.114 |
| Albumin (g/dl) | 3.02 ± 0.5 | 3.01 ± 0.54 | 2.6–4 | 0.997 |
| Total protein (g/dl) | 7.17 ± 0.9 | 7.93 ± 0.95 | 6.5–8.8 | 0.005 |
| A:G (g:g) | 0.76 ± 0.19 | 0.65 ± 0.21 | 0.52–1.19 | 0.051 |
| Creatinine (mg/dl) | 1.54 (0.41–11.77) | 1.71 (0.78–31.46) | 0.8–1.8 | 0.375 |
| Urea (mg/dl) | 63 (13–533) | 59 (26–600) | 30–65 | 0.773 |
| Phosphate (mg/dl) | 4.8 (1.8–15.8) | 5.1 (3.4–15.2) | 2.5–6.2 | 0.547 |
| Potassium (mEq/l) | 4.3 (2.6–7.4) | 4.4 ± 0.6 | 3.4–5.1 | 0.418 |
| Sodium (mEq/l) | 152 (136–168) | 151 ± 4 | 145–155 | 0.720 |
| Chloride (mEq/l) | 117 (97–127) | 116 ± 4 | 110–123 | 0.561 |
| Magnesium (mg/dl) | 2.3 (1.5–4.6) | 2.5 ± 0.3 | 1.9–2.8 | 0.259 |
| Total calcium (mg/dl) | 9.8 (6.7–13.1) | 9.8 ± 0.7 | 8.5–10.5 | 0.948 |
| SAA (µg/dl) | 8 (1–308) | 12 (1–202) | 0–10 | 0.724 |
| Serum protein electrophoresis | ||||
| Albumin (g/dl) | 2.80 ± 0.61 | 2.91 ± 0.66 | 2.10–3.30 | 0.443 |
| Albumin (%) | 39 ± 8 | 37 ± 9 | – | 0.492 |
| α1-globulin (g/dl) | 1.18 (0.02–3.62) | 1.16 (0.09–1.63) | 0.1–0.8 | 0.710 |
| α1-globulin (%) | 16 (0–54) | 15 (1–20) | – | 0.057 |
| α2-globulin (g/dl) | 0.83 (0.33–2.87) | 0.81 (0.61–3.3) | 0.58–1.05 | 0.573 |
| α2-globulin (%) | 12 (6–39) | 10 (7–40) | – | 0.557 |
| β1-globulin (g/dl) | 0.56 (0.21–1.29) | 0.59 ± 0.12 | 0.45–0.80 | 0.507 |
| β1-globulin (%) | 8 (3–20) | 7 ± 2 | – | 0.183 |
| β2-globulin (g/dl) | 0.43 (0.14–1.66) | 0.55 (0.32–1.21) | 0.35–0.75 | 0.013 |
| β2-globulin (%) | 6 (2–25) | 7 ± 2 | – | 0.143 |
| γ-globulin (g/dl) | 1.03 (0.02–2.79) | 1.37 (0.82–3.44) | 0.60–1.30 | 0.003 |
| γ-globulin (%) | 15 (0–33) | 20 ± 7 | – | 0.014 |
| A:G (g:g) | 0.67 ± 0.2 | 0.63 ± 0.23 | – | 0.489 |
| Urinalysis | ||||
| USG | 1026 (1008–1084) | 1039 ± 23 | >1040 | 0.428 |
| Urine creatinine (mg/dl) | 105 (14–437) | 246 ± 186 | – | 0.042 |
| Urine protein (mg/dl) | 46 (2–2188) | 94 (8–565) | 0–0.4 | 0.114 |
| UPC (mg:mg) | 0.35 (0.04–38.58) | 0.28 (0.12–10.63) | <0.2 | 0.750 |
Data are mean ± SD or median (range). Values in bold indicate statistical significance
RI = reference interval; RBCs = red blood cells; WBCs = white blood cells; Hb = haemoglobin; Hct = haematocrit; MCV = mean cell volume; MCH = mean cell haemoglobin; MCHC = mean cell haemoglobin concentration; MPV = mean platelet volume; RDW = red cell distribution width; ALT = alanine aminotransferase; AST = aspartate aminotransferase; ALP = alkaline phosphatase; GGT = gamma-glutamyl transferase; A:G = albumin:globulin ratio; SAA = serum amyloid A; USG = urine specific gravity; UPC = urine protein:creatinine ratio