Table 1.
Comparison between groups of high vs. low zonulin serum levels.
| Variable | Low Zonulin (n = 14) |
High Zonulin (n = 13) |
p-Value | |
|---|---|---|---|---|
| Age (years) | 60.36 (SD = 12.68) | 68.1 (SD = 6.37) | 0.046 a | |
| Gender (male/female) | 13:1 | 1:12 | 0.000 b | |
| Karnofsky < 70 | 1 (7.1%) | 2 (15.4%) | 0.596 b | |
| Contrast enhancement | Periferic | 9 (64.3%) | 6 (46.2%) | 0.449 b |
| Heterogeneous | 5 (35.7%) | 7 (53.8%) | ||
| Contrast enhancement volume (cc) | 24.74 (SD = 18.06) | 20.99 (SD = 14.62) | 0.593 a | |
| Edema volume (cc) | 51.15 (SD = 28.36) | 55.37 (SD = 38.13) | 0.923 a | |
| Necrosis volume (cc) | 15.63 (SD = 13.94) | 5.37 (SD = 4.31) | 0.099 a | |
| Resection | Partial | 2 (14.3%) | 6 (46.2%) | 0.132 c |
| Subtotal | 4 (28.6%) | 1 (7.7%) | ||
| Total | 8 (57.1%) | 6 (46.2%) | ||
| Ki67 (%) | 28.54 (SD = 13.91) | 21.0 (SD = 12.79) | 0.181 a | |
| MGMT methylation | 7 (50.0%) | 8 (66.7%) | 0.453 b | |
| Progression-free survival (months) | 10.5 [6.6–14.3] | 3.7 [3.3–4.1] | 0.130 d | |
a Mann–Whitney U. b Fisher’s Exact test. c Chi-Square. d Log-Rank test.