Table 2.
Comparison between groups of high vs. low zonulin expression in tumoral specimens.
| Variable | Low Zonulin (n = 11) |
High Zonulin (n = 10) |
p-Value | |
|---|---|---|---|---|
| Age (years) | 61.55 (SD = 14.00) | 69.5 (SD = 7.66) | 0.341 a | |
| Gender (male/female) | 4:7 | 6:4 | 0.395 b | |
| Karnofsky < 70 | 2 (18.2%) | - | 0.476 b | |
| Contrast enhancement | Periferic | 6 (54.5%) | 2 (20.0%) | 0.183 b |
| Heterogeneous | 5 (45.5%) | 8 (80.0%) | ||
| Contrast enhancement volume (cc) | 12.91 (SD = 10.31) | 28.13 (SD = 14.20) | 0.020 a | |
| Edema volume (cc) | 42.44 (SD = 19.14) | 79.78 (SD = 43.13) | 0.037 a | |
| Necrosis volume (cc) | 6.50 (SD = 9.81) | 10.85 (SD = 9.01) | 0.152 a | |
| Resection | Partial | 1 (9.1%) | 1 (10.0%) | 0.990 c |
| Subtotal | 2 (18.2%) | 2 (20.0%) | ||
| Total | 8 (72.7%) | 7 (70.0%) | ||
| Ki67 (%) | 26.2 (SD = 17.62) | 28.6 (SD = 22.17) | 0.880 a | |
| MGMT methylation | 6 (54.5%) | 4 (40.0%) | 0.670 b | |
| Progression-free survival (months) | 6.6 [2.4–10.9] | 3.3 [0.0–6.5] | 0.024 d | |
a Mann–Whitney U. b Fisher’s Exact test. c Chi-Square. d Log-Rank test.